Results 91 to 100 of about 63,753 (337)

Arterial traffic signal optimization: a person-based approach [PDF]

open access: yes, 2013
This paper presents a traffic responsive signal control system that optimizes signal settings based on minimization of person delay on arterials. The system's underlying mixed integer linear program minimizes person delay by explicitly accounting for the
Aboudolas, K.   +2 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Assessing Public Transit Network Efficiency and Accessibility in Johor Bahru and Penang, Malaysia: A Data-Driven Approach

open access: yesResults in Engineering
This study conducts a comprehensive analysis of public bus transit networks in Johor Bahru and Penang, Malaysia, using General Transit Feed Specification (GTFS) data.
Mahbub Hassan   +5 more
doaj   +1 more source

Towards In-Transit Analytics for Industry 4.0

open access: yes, 2017
Industry 4.0, or Digital Manufacturing, is a vision of inter-connected services to facilitate innovation in the manufacturing sector. A fundamental requirement of innovation is the ability to be able to visualise manufacturing data, in order to discover ...
Ali, Muhammad   +3 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Demand-responsive public transportation re-scheduling for adjusting to the joint leisure activity demand

open access: yesInternational Journal of Transportation Science and Technology, 2016
Fixed daily trips such as trips to work/school have fixed departure/arrival times and destination points. The recurrent nature of fixed activities facilitates individuals on making more well-informed decisions about the transport mode selection.
Konstantinos Gkiotsalitis   +1 more
doaj   +1 more source

Transportation Futures: Policy Scenarios for Achieving Greenhouse Gas Reduction Targets, MNTRC Report 12-11 [PDF]

open access: yes, 2014
It is well established that GHG emissions must be reduced by 50% to 80% by 2050 in order to limit global temperature increase to 2°C. Achieving reductions of this magnitude in the transportation sector is a challenge and requires a multitude of policies ...
Kay, Andrew I.   +3 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Development of an Algorithm for Optimal Demand Responsive Relocatable Feeder Transit Networks Serving Multiple Trains and Stations

open access: yesUrban Rail Transit, 2019
Although demand responsive feeder bus operation is possible with human-driven vehicles, it has not been very popular and is mostly available as a special service because of its high operating costs due to intensive labor costs as well as requirement for ...
Young-Jae Lee   +3 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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