Results 121 to 130 of about 63,753 (337)
Design of a Demand-Responsive Transit System
, 2007 This research investigates the feasibility of offering demand-responsive transit (DRT) service to the general public in situations of low demand density. The study region is AC Transit District 2 which consists of the cities of Fremont and Newark, California.We developed a methodology to evaluate operating efficiencies of existing bus lines and line ...
Li, Yuwei +3 more
openaire +1 more source
Research on Fleet Size of Demand Response Shuttle Bus Based on Minimum Cost Method
Applied SciencesDemand-responsive connector services (DRC) are an important means to improve the current mobility connection problem. In this study, we develop a hybrid model for the minimization of total system cost for demand response shuttle buses, which includes ...
Xianglong Sun, Yucong Zu
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Is sea-basing a viable method of providing logistic support to the UK amphibious force? [PDF]
, 2000 Maritime power has traditionally been a central part of the UK’s defence planning and is well suited to supporting a wide range of military operations. The littoral area has always created problems for naval planners as most landings historically have ...
Antill, Peter D. +2 more
core
, 2019 We propose a ridesharing strategy with integrated transit in which a private on-demand mobility service operator may drop off a passenger directly door-to-door, commit to dropping them at a transit station or picking up from a transit station, or to both
Chow, Joseph Y. J. +3 more
core +1 more source
An Analytical Model for the Many-to-One Demand Responsive Transit Systems [PDF]
, 2019 Di Huang +3 more
openalex +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Optimizing travel costs of feeder-integrated public transport system: A methodology
Transportation Research Interdisciplinary PerspectivesCanada, with a substantial contribution from the personal transport sector, is a major per capita greenhouse gas emitter. This study advocates a sustainable 3-echelon transportation system, integrating Public Transit (PuT) and demand-responsive transit ...
Mysore Narasimhamurthy Sharath +4 more
doaj +1 more source
A Simulation Model for Evaluating Demand Responsive Transit: Real-Time Shared-Taxi Application [PDF]
, 2012 Jaeyoung Jung
openalex +1 more source