Results 141 to 150 of about 63,753 (337)

Measuring the price responsiveness of gasoline demand [PDF]

open access: yes
This paper develops a new method for estimating the demand function for gasoline and the deadweight loss due to an increase in the gasoline tax. The method is also applicable to other goods. The method uses shape restrictions derived from economic theory
Joel Horowitz   +2 more
core  

Long-Term Low Income Housing Tax Credit Policy Questions [PDF]

open access: yes, 2010
Discusses Low Income Housing Tax Credit policy questions such as whether to target the lowest-income families, issues such as geographic gaps in tax credit investment demand, and ongoing capital needs and asset management for LIHTC ...

core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Government Failure in Urban Transportation [PDF]

open access: yes
This paper assesses governmental performance in its investment, provision and regulation of urban transportation. Attention is given to public bus and rail transit and road transportation.
Clifford Winston
core  

No Californian Left Behind: Clean and Affordable Transportation Options for All Through Vehicle Replacement [PDF]

open access: yes, 2014
As California focuses in on new, high-tech, best-in-class transportation strategies, it risks leaving behind an important subset of households and communities who could most benefit from the transition to a cleaner, cheaper, and more sustainable ...
Cole Wheeler, Jesse Morris, Kate Gordon
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Benefits and harms of DRT in suburban areas – analysis of user motivations, ridership, and side effects of an app-based demand-responsive transit

open access: yesJournal of Urban Mobility
Since the rebirth of demand-responsive transit (DRT) after 2010 many failed and discontinued initiatives have been observed. The issues range from inadequate technology, ill-defined spatial and temporal conditions, to missing knowledge of user ...
Bartosz Bursa   +3 more
doaj   +1 more source

Transportation for an Aging Population: Promoting Mobility and Equity for Low-Income Seniors [PDF]

open access: yes, 2018
This study explores the travel patterns, needs, and mobility problems faced by diverse low-income, inner-city older adults in Los Angeles in order to identify solutions to their mobility challenges.
Brozen, Madeline   +3 more
core   +1 more source

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