Results 151 to 160 of about 63,753 (337)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Mobility service design via joint optimization of transit networks and demand-responsive services

, 2021
Yining Liu, Yanfeng Ouyang
openalex   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Intelligent vehicle platooning transit: System design, operations management, and field and simulation experiments

Transport Economics and Management
This paper serves as a technical review on an emerging demand-responsive, vehicle platoon-based, exclusive lane-delimited mass transit system, which is officially named Intelligent Vehicle Platooning Transit (IVPT).
Chi Xie, Ziyu Zhang, Aijing Su, Bing Wu
doaj   +1 more source

THE DIFFERENCE BETWEEN ACTUAL USER AND PREDICTED USER OF DEMAND RESPONSIVE TRANSIT

, 2012
Honami TAKANO, Akinori Morimoto
openalex   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Factors affecting use of fixed-route and demand-responsive services in a university community

Discover Cities
Shared mobility systems are declining in university communities, despite its reputation as an economical, sustainable, and appealing alternative to private cars.
Muhammad Arif Khan, Roya Etminani-Ghasrodashti, Apurva Pamidimukkala, Sharareh Kermanshachi, Jay Michael Rosenberger, Greg Hladik   +5 more
doaj   +1 more source

The Relationship Between Built Environment and the Ridership of Demand Responsive Transit Using Direct Demand Model: A Case Study of Yeongjong Island, Incheon

, 2023
Jaehyung LEE, Jiwon KIM, Jin-Hyuk Chung, Jinhee KIM   +3 more
openalex   +1 more source

Adaptive Transit Design: Optimizing Fixed and Demand Responsive Multi-Modal Transportation via Continuous Approximation [PDF]

, 2021
Giovanni Calabro', Andrea Araldo, Simon Oh, Ravi Seshadri, Giuseppe Inturri, Moshe Ben‐Akiva   +5 more
openalex   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source