Results 281 to 290 of about 6,436,519 (354)

Managing ecosystem service deficits through ecological-social prioritization. [PDF]

Sci Rep
Khosravi Mashizi A.
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

A machine learning framework for long-term forecasting of spare part demand in end-of-life product scenarios. [PDF]

Sci Rep
B SN, Reddy BVS, Sujan VSS, Sastry CC, Krishnaiah J, Jitpichitchai S.   +5 more
europepmc   +1 more source

Location allocation and capacity optimization for a PV and battery integrated hybrid community electric vehicle charging station. [PDF]

Sci Rep
Kayal P, Braciník P.
europepmc   +1 more source

Financial Literacy, Retirement Planning, and Demand for Life Insurance: Evidence from Lagos State-owned Tertiary Institutions

Sunday Stephen Ajemunigbohun, Rasheed Olawale Azeez   +1 more
openalex   +2 more sources

A Multi Tuning-Frequency Passive/On-demand Active Pendulum Tuned Mass Damper

Mohamed A. Eltaeb, Mustafa Ali Esmaio, Reza Kashani   +2 more
openalex   +1 more source

Demande d’analyse, demande de jouir

Analyse Freudienne Presse, 2015
openaire   +2 more sources

The role of external factors in shaping the supply and demand of general practitioners in Iran: a qualitative study. [PDF]

BMC Prim Care
Amiresmaili M, Mehrolhassani MH, Iranmanesh M.   +2 more
europepmc   +1 more source

THE IMPACT OF DESIGN VARIABLES ON THE HEAT DEMAND OF A RESIDENTIAL BUILDING IN THE COLD REGION

Mehdi Mirza Goltabar Roshan
openalex   +2 more sources

Coupling coordination evaluation and influencing factors analysis of older adult care service resource supply and demand in China. [PDF]

Front Public Health
Guo L, Wei H, Tao Q, Chen K.
europepmc   +1 more source