Results 81 to 90 of about 1,045,215 (267)

Multi-objective optimization method for power supply and demand balance in new power systems

International Journal of Electrical Power & Energy Systems
The large amount of source and load uncertainty in new power systems poses challenges to the optimization of power supply and demand balance. The traditional optimization methods have not fully considered the uncertainty characteristics of different ...
Jiaxi Li, Ming Wen, Zhuomin Zhou, Bo Wen, Zongchao Yu, Haiwei Liang, Xinyang Zhang, Yue Qin, Chufan Xu, Hongyi Huang   +9 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Effective Development and Management Strategy for Distributed Smart Grids Based on Collective Intelligence

Zhongguo dianli
To overcome the challenge of accurately investing in the construction strategies of distributed smart grids under different resource endowments, an efficient development and management strategy for distributed smart grids based on collective intelligence
Zongchao YU, Ming WEN, Xianghua LI, Xintao XIE, Hongming YANG   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Multi-objective optimization method for medium and long-term power supply and demand balance considering the spatiotemporal correlation of source and load

Energy Strategy Reviews
The medium and long-term supply-demand imbalance of the power system in the context of the new power system is becoming more and more prominent due to the fluctuation and intermittency brought about by the high proportion of new energy sources connected ...
Jiaxi Li, Zhuomin Zhou, Ming Wen, Hongyi Huang, Bo Wen, Xinyang Zhang, Zongchao Yu, Haiwei Liang   +7 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Stability analysis and parameter optimization of SVG in renewable energy collection stations based frequency-domain admittance matrix

Frontiers in Energy Research
Equipping a renewable energy collection station with Static Var Generator (SVG) contributes to the enhancement of the power quality, and system stability. To efficiently achieve the analysis of grid-connected stability and multi-parameter optimization of
Changyu Li, Changyu Li, Wenqing Lu, Wenqing Lu, Huan Xie, Huan Xie, Jie Tao, Pengwei Chen, Xin Chen, Xiuyi Shang   +9 more
doaj   +1 more source