Results 161 to 170 of about 4,278,572 (308)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

A City-scale and Harmonized Dataset for Global Electric Vehicle Charging Demand Analysis. [PDF]

Sci Data
Guo Z, You L, Zhu R, Zhang Y, Yuen C.
europepmc   +1 more source

Sex Differences in the Reward-Enhancing Effects of Nicotine on Ethanol Reinforcement: A Reinforcer Demand Analysis. [PDF]

Nicotine Tob Res, 2020
Barrett ST, Thompson BM, Emory JR, Larsen CE, Pittenger ST, Harris EN, Bevins RA.   +6 more
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Demand analysis of perioperative nursing service needs for patients with cervical spondylosis based on the Kano model: a cross-sectional study. [PDF]

BMC Nurs
Hu L, Wang L, Wang Y, Huang J, Dong P, Luo C.   +5 more
europepmc   +1 more source

The Effect of Increased Energy Prices on Agriculture: A Differential Supply Approach [PDF]

The increase in energy prices between 2004 and 2007 has several potential consequences for aggregate agriculture in the U.S. We estimate the derived input demand elasticities for energy as well as capital, labor, and materials using the differential ...
Livanis, Grigorios T., Moss, Charles B., Schmitz, Andrew   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Data-driven demand analysis and design reliability study of critical components of complex products. [PDF]

PLoS One
Meng Z, Wang Z, Gao D, Lu W.
europepmc   +1 more source

Demand Analysis and Management Suggestion: Sharing Epidemiological Data Among Medical Institutions in Megacities for Epidemic Prevention and Control. [PDF]

J Shanghai Jiaotong Univ Sci, 2020
Cai Q, Mi Y, Chu Z, Zheng Y, Chen F, Liu Y.   +5 more
europepmc   +1 more source

THE CALIBRATION OF INCOMPLETE DEMAND SYSTEMS IN QUANTITATIVE ANALYSIS [PDF]

We introduce an easily implemented and flexible calibration technique for partial demand systems, combining recent developments in incomplete demand systems and a set of restrictions conditioned on the available elasticity estimates.
Beghin, John C., Bureau, Jean-Christophe, Drogue, Sophie   +2 more
core   +1 more source