Results 131 to 140 of about 1,054,066 (309)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

ESTIMATION OF A DEMAND SYSTEM WITH LIMITED DEPENDENT VARIABLES [PDF]

open access: yes
The study employs the full-information maximum-likelihood method to estimate a censored translog demand system. U.S. household consumption of steak, roast, and ground beef are used to demonstrate the application of the estimation procedure.
Huang, Chung L., Yen, Steven T.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Household Water Demand Estimation using Micro-Level Data [PDF]

open access: yes
La Reunion Island is facing to specific difficulties in supplying drinking water. In the western part of this french departement drincking water is lacking.
Fabrizio Carlevaro   +3 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A Reservation Aggregation Framework Design for Demand Estimation

open access: yesActa Polytechnica, 2006
Effective management practices in the tourism and hotel area have seldom been more important than at the present time. Pricing decisions cannot be taken without serious thought. IT has provided the opportunity for a customer to make a quick market search
T. Vítek, D. Pachner
doaj  

Field weed population models: a review of approaches and application domains [PDF]

open access: yes, 2005
We evaluated models of weed population dynamics based on an analysis of their assumptions, biological rationale, flexibility, documentation, accessibility, demand for parameter estimation and documented validity.
Bastiaans, L.   +2 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Robust Estimation of the Joint Consumption / Asset Demand Decision [PDF]

open access: yes
The paper proposes an instrumental variables version of the Huber estimator as an alternative to the IV-Krasker Welsch estimator. The IV-Huber estimator is analytically and computationally much simpler than IV-Krasker Welsch.
Marjorie Flavin
core  

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