Results 141 to 150 of about 1,054,066 (309)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Connected Substitutes and Invertibility of Demand [PDF]
We consider the invertibility of a nonparametric nonseparable demand system. Invertibility of demand is important in several contexts, including identification of demand, estimation of demand, testing of revealed preference, and economic theory requiring
Amit Gandhi, Philip Haile, Steven Berry
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Estimation of Consumer Demand Functions When the Observed Prices Are the Same for All Sample Units [PDF]
With the advent of the almost ideal demand system (AIDS) of Deaton and Muellbauer, the estimation of consumer demand functions revolves around specifications that use flexible functional forms of the indirect utility function.
Paris, Quirino
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
A Practical Multi-Sensor Cooling Demand Estimation Approach Based on Visual, Indoor and Outdoor Information Sensing. [PDF]
Sensors (Basel), 2018 Wang J, Tse NCF, Poon TY, Chan JYC.
europepmc +1 more source
Some neglected issues in food demand analysis: retail-level demand, health information and product quality [PDF]
Food demand analysis is dominated by the econometric estimation of demand systems based on aggregate market data and steady progress has been made in analytical techniques. Yet some issues have been neglected in food demand analysis which are crucial for
Herrmann, Roland, Roeder, Claudia
core +1 more source
Estimating Time Demand Elasticities Under Rationing. [PDF]
, 2004 A multivariate extension of the standard labour supply model in presented. In the multivariate time allocation model leisure is disaggregated into a number of non market activities including sports, volunteer work and home production. Using data from the 2000 UK Time Use Survey, a linear expenditure system is estimated, allowing corner solutions in the
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Integrating Optimal Heterogeneous Sensor Deployment and Operation Strategies for Dynamic Origin-Destination Demand Estimation. [PDF]
Sensors (Basel), 2017 Zhu S, Guo Y, Chen J, Li D, Cheng L.
europepmc +1 more source