Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Day-ahead optimal dispatch considering demand response compensation and carbon trading under uncertain environment. [PDF]
PLoS OneYe Z, Liang D, Wang M, Chen L.
europepmc +1 more source
Region-wise evaluation of price-based demand response programs in Japan's wholesale electricity market considering microeconomic equilibrium. [PDF]
iScience, 2023 Malehmirchegini L +2 more
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
An optimized demand response framework for enhancing power system reliability under wind power and EV-induced uncertainty. [PDF]
Sci RepPakbin H, Karimi A, Hassanzadeh MN.
europepmc +1 more source
Scheduling and Sizing of Campus Microgrid Considering Demand Response and Economic Analysis. [PDF]
Sensors (Basel), 2022 Bin L +6 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Day-ahead economic dispatch of wind-integrated microgrids using coordinated energy storage and hybrid demand response strategies. [PDF]
Sci RepMeng Q +4 more
europepmc +1 more source
Datasets on South Korean manufacturing factories' electricity consumption and demand response participation. [PDF]
Sci Data, 2022 Lee E, Baek K, Kim J.
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source