Results 131 to 140 of about 4,741 (297)
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Dynamics of modal choice of heterogeneous travelers with responsive transit services
, 2016 In this paper, we investigate travelers’ day-to-day modal choice in a bi-modal transportation system with responsive transit services under various economic objectives.
Yang, Hai, Li, Xinwei
core +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
, 2003 This paper presents a methodology for the joint optimization of cost, service and life-cycle environmental consequences in vehicle routing and scheduling for a demand-responsive (paratransit or dial-a-ride) transit system.
Dessouky, M, RAHIMI, M, Weidner, M
core
Benchmarking Best Practices of Demand Responsive Transit Systems [PDF]
, 2003 Over the past 10 years, operating expenses for Demand Responsive Transit have more than doubled as demand for this mandated service has expanded. Many advanced technologies and management practices have been proposed and implemented to improve the ...
Dessouky, Maged +2 more
core
Journal of Urban MobilitySince the rebirth of demand-responsive transit (DRT) after 2010 many failed and discontinued initiatives have been observed. The issues range from inadequate technology, ill-defined spatial and temporal conditions, to missing knowledge of user ...
Bartosz Bursa +3 more
doaj +1 more source
Optimal Design of Demand-Responsive Feeder Transit Services [PDF]
, 2009 The general public considers Fixed-Route Transit (FRT) to be inconvenient while Demand-Responsive Transit (DRT) provides much of the desired flexibility with a door-to-door type of service. However, FRT is typically more cost efficient than DRT to deploy.
Li, Xiugang
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Demand-Sensitive Candidate Route Generation Algorithm
, 2016 Demand satisfaction is a key component that reflects the quality of public transit from the passenger’s perspective, whereas cost minimization is considered a main objective of transit agencies.
Davanzo, Elis Reny A. +1 more
core +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source