Results 101 to 110 of about 2,387,314 (300)
Data model for Demand Side Management [PDF]
Demand Side Management (DSM) is a portfolio of measures to improve the energy system mainly at the consumption level. In this paper we propose a data model for DSM stating from the optimization methods approach in SMARTRADE project from different ...
Simona-Vasilica OPREA, Osman Bulent TOR
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
School Choice in Chile: Looking at the Demand Side [PDF]
How do parents choose among schools when they are allowed to do so? In this paper, we analyze detailed information of 70,000 fourth-graders attending about 1,200 publicly subsidized schools in the context of the Chilean voucher system.
Andrés Hernando, Francisco Gallego
core
The Global Organic Food Market and Transformation Deductive Definition of Empiric Indicators The Demand Explanation The Institutional Explanation & Comparative Country Report: Denmark versus Sweden [PDF]
The present study is part of the project “Public Policies and Demand for Organic Food: An International Comparison of Policy Effects and Policy Determinants” (COP). It is carried out in WP II that concerns the supply-side policies and demand. In the WP
Rasmussen, Ole Horn
core
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
With the increasing penetration of renewable energy sources, there has been a profound structural transformation in electricity markets, particularly in the operational paradigm where demand-side resources participate in market mechanisms. This evolution
Lefeng CHENG +5 more
doaj +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Raising primary school enrollment in developing countries [PDF]
Few policies are as universally accepted as raising primary school enrolment in developing countries, but the policy levers for achieving this goal are not straight forward.
Handa, Sudhanshu
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source

