Results 111 to 120 of about 11,791,712 (289)

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Energy Planning in Small Municipalities Based on Monitoring Results and Demand Side Management

Recent estimates state that the European Union is on course to achieve only half of the 20% energy consumption reduction target by 2020. As the first governmental stakeholders involved in the implementation of energy saving initiatives, municipalities ...
Rošā, Marika, Blumberga, Andra, Blumberga, Dagnija, Barisa, Aiga   +3 more
core  

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

Research on the optimal operation of a prosumer micro energy network centred on data centres

IET Renewable Power Generation
As the share of intermittent and fluctuating renewable energy sources in the power system continues to increase, demand‐side resources must be utilized to enhance the real‐time balance of power generation and supply.
Yuanshi Zhang, Yiwu Ge, Shunjiang Wang, Weiqi Pan, Yiwen Feng, Peng Qiu   +5 more
doaj   +1 more source

Systems Thinking and Systems Dynamics Approach to Demand Side Management

Systems and Computing
Context: Demand Side Management (DSM) provides utilities with tools to modify end users’ consumption patterns, helping reduce peak demand, alleviate stress on the power grid, and even support with the integration of renewables.
Donnell Joe Nagoma, Kameswara Musti
doaj   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

Positive Impacts of Demand and Source Management on Improving Eco‐Emission Constraints of Combined Hydrogen, Heat and Power

IET Smart Grid
Cogeneration sources are good choices for meeting the diversity of consumers energy demand. Recently, with the introduction of the microgrid (MG) concept, to increase security, reliability, and quality of the system, loads are fed locally by low‐scale ...
Mojtaba Pirmohammad Talatape, Reza Ghanizadeh, Sajad Bagheri, Mohammad Reza Miveh   +3 more
doaj   +1 more source

Demand response in the residential sector: A critical feature of sustainable electricity supply in New Zealand [PDF]

, 2008
The world summit on sustainable development in Johannesburg concluded that changing unsustainable patterns of energy use is a key area for global action to ensure survival of our planet.
Krumdieck, S., Gyamfi, S., Brackney, L.
core  

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source