Results 111 to 120 of about 257,107 (328)

Vestiges de bornage antique en Île-de-France et en Picardie. La question des dépôts de vases dans les fossés

open access: yesArchéopages, 2013
Works on ancient surveying (for example by Siculus Flaccus in the second century AD) refer to practices used when establishing boundaries that involved the burial of non-perishable goods in the ground, marked by surface markers.
Véronique Pissot   +6 more
doaj   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

open access: yesAdvanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu   +25 more
wiley   +1 more source

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

open access: yesAdvanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan   +9 more
wiley   +1 more source

Demarcating normative political theory from political science – and why it matters methodologically (or cheering for a hybrid empirical–normative methodology in political theory)

open access: yesPolitical Research Exchange
Scholars debating the methodology of political theory present arguments regarding the function of political science within/for normative political theory. We suggest a demarcation principle separating the core of normative political theory from political
Nahshon Perez
doaj   +1 more source

Diagnosing Pseudoscience – by Getting Rid of the Demarcation Problem

open access: yesJournal for General Philosophy of Science, Zeitschrift für allgemeine Wissenschaftstheorie, 2021
M. Boudry
semanticscholar   +1 more source

Phase Diagrams and Piezoelectric Properties of Wurtzite Al1−x−yScxGdyN Heterostructural Alloys

open access: yesAdvanced Science, EarlyView.
This study demonstrates ferroelectricity and piezoelectric properties improvement of quaternary wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films, guided by density functional theory calculations. Wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films have a high optical bandgap, enhanced piezoelectric ...
Julia L. Martin   +11 more
wiley   +1 more source

Beyond Representation: Philosophy And Poetic Imagination [PDF]

open access: yes, 1996
The essays in this volume explore the ways in which traditional philosophical problems about self-knowledge, self-identity, and value have migrated into literature since the Romantic and Idealist periods.
Eldridge, Richard Thomas
core   +2 more sources

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

open access: yesAdvanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen   +15 more
wiley   +1 more source

Indigenous sciences are not pseudoscience

open access: yesIdeas in Ecology and Evolution, 2014
Given how difficult it is to define science, it is surprising how readily many people consider Indigenous sciences to be pseudoscience. I review definitions of indigenous science, as well as science and pseudoscience.
Root Gorelick
doaj  

What’s the Point?: An Exploration of Students’ Motivation to Learn in a First-Year Seminar [PDF]

open access: yes, 2011
This qualitative case study explores how undergraduate students and their instructor made meaning of students’ motivation to learn in a one-credit, pass/fail first-year seminar.
Jessup-Anger, Jody E.
core   +1 more source

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