Results 211 to 220 of about 61,459 (308)

Risk–Benefit of Phase 2 Monotherapy Trials in Adult Solid Cancers: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Cancer, EarlyView.
The therapeutic status of drug administration in phase 2 cancer trials is ambiguous, as these studies test efficacy without strong evidence of clinical benefit. Nonetheless, patients face meaningful risks. This review compared efficacy and safety of monotherapy drugs in phase 2 and phase 3 trials across six cancer types.
Charlotte Ouimet   +2 more
wiley   +1 more source

Basic Self-disorders Across Psychiatric Diagnoses and Risk Syndromes: An Updated Meta-analysis. [PDF]

open access: yesSchizophr Bull
Estradé A   +12 more
europepmc   +1 more source

Laparoscopic Resection of Caudate Lobe Liver Tumors in Clinical Practice

open access: yesiNew Medicine, EarlyView.
ABSTRACT The caudate lobe (Couinaud segment I), owing to its deep location in the posterosuperior liver, intimate encirclement by the inferior vena cava (IVC), and close adjacency to the hepatic hilum and major hepatic veins, presents a formidable anatomical challenge for resection.
Dingde Ye   +4 more
wiley   +1 more source

Deep learning‐based prediction of cervical lymph node metastasis and genetic alterations from whole‐slide images of thyroid cancer frozen sections

open access: yesInterdisciplinary Medicine, EarlyView.
Deep learning models accurately predict cervical lymph node metastasis and key genetic mutations (BRAF/TERT) directly from thyroid cancer frozen sections. This AI‐driven pipeline provides a rapid real‐time tool to guide intraoperative surgical decisions, helping to optimize surgical extent and prevent both over‐ and under‐treatment without the need for
Mingxing Qiu   +20 more
wiley   +1 more source

Impact of Geography on Institutions in Agricultural and Nomadic Societies

open access: yesInternational Studies of Economics, EarlyView.
ABSTRACT How geography affects the choice of institutions is studied in a theoretical model. In this model, nations are located around a circle. Rulers compete through choosing tax rates, the level of military spending, and the degree of formality of institutions. Geographic condition is captured by population density.
Haiwen Zhou
wiley   +1 more source

Who Am I When You're a Bot? Relational Identity and AI Companions

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT Self‐conceptions provide a framework through which we can make sense of ourselves, interpret and navigate the world, plan our lives, and relate to others. Relational influences can greatly shape them, for instance, when others react to us or offer advice. What if this ‘other’ is not a human being, but an AI?
Muriel Leuenberger
wiley   +1 more source

Do Linking‐Expression Substitutions Mitigate Deterministic Interpretations of Genetic Information?

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT It is a common concern that broader audiences interpret scientific information about the genetic correlates and causes of complex human traits in an overly deterministic manner. A frequently proposed way to address this issue is to carefully select the linking expressions used to describe gene–trait relationships when communicating genetic ...
Riin Kõiv
wiley   +1 more source

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