Chromoblastomycosis Due to a Never-before-Seen Dematiaceous Fungus in a Kidney Transplant Patient
Microorganisms, 2021 Chromoblastomycosis is a neglected fungal infection of the epidermis and subcutaneous tissue that predominates in tropical areas and results from the traumatic inoculation of environmental dematiaceous filamentous fungi.
Hélène Guegan +4 more
doaj +2 more sources
Anales del Jardín Botánico de Madrid, 2009 Repetophragma calongeii sp. nov., a dematiaceous hyphomycete found on unidentified dead wood collected in the Pagoeta Natural Park, Spain, is described and illustrated.
Carolina Silvera-Simón +4 more
doaj +3 more sources
Characterisation of putative class 1A DHODH-like proteins from Mucorales and dematiaceous mould species. [PDF]
PLoS ONE, 2023 Olorofim is a new antifungal in clinical development which has a novel mechanism of action against dihydroorotate dehydrogenase (DHODH). DHODH form a ubiquitous family of enzymes in the de novo pyrimidine biosynthetic pathway and are split into class 1A,
Corinne Pinder +4 more
doaj +3 more sources
Indian Journal of OphthalmologyPurpose: Dematiaceous fungi, the third most common causative organism of fungal keratitis, constitute 3.5% to 43.5% of fungal keratitis worldwide.
Niruban Ganesan +4 more
doaj +2 more sources
Deep anterior lamellar keratoplasty in dematiaceous keratomycosis
Journal of Clinical Ophthalmology and Research, 2016 Deep anterior lamellar keratoplasty is a technique which has been used effectively to treat anterior stromal corneal opacities, with the obvious benefit of preserving host endothelium. This report documents its use in a case of dematiaceous keratomycosis
Shilpa Ajit Joshi +2 more
doaj +2 more sources
Disseminated Phaeohyphomycosis Due to <i>Alternaria alternata</i> in a Liver Transplant Recipient: Successful Treatment With Isavuconazole, a Case Report and Literature Review. [PDF]
Case Rep TransplantPhaeohyphomycoses are a heterogeneous group of diseases caused by several genera of pigmented fungi, also called dematiaceous fungi. These organisms are increasingly recognized as emerging opportunistic pathogens in immunocompromised patients, particularly solid organ transplant recipients. Among them, Alternaria is the most frequently associated genus,
Tapia-Villacis S +3 more
europepmc +2 more sources
Time-resolved multi-omics reveals macrophage-centered immunometabolic remodeling in cutaneous dematiaceous fungal infection. [PDF]
Front ImmunolBackground Dematiaceous fungi cause chronic, invasive cutaneous infections that are difficult to eradicate and frequently relapse despite antifungal therapy.
Fu Y +7 more
europepmc +2 more sources
Pheohyphomycosis in Renal Transplant Recipient Presenting as a Rare Case of Submandibular Salivary Gland Swelling [PDF]
Journal of Clinical and Diagnostic Research, 2016 Renal transplant patients are at high risk of developing various infections causing morbidity and mortality. Invasive fungal infection has been recognized as a significant complication of organ transplantation.
Rashmi D. Patel +2 more
doaj +1 more source
BLASTP results for DHODH in dematiaceous species.
, 2023 Olorofim is a new antifungal in clinical development which has a novel mechanism of action against dihydroorotate dehydrogenase (DHODH). DHODH form a ubiquitous family of enzymes in the de novo pyrimidine biosynthetic pathway and are split into class 1A,
Corinne Pinder (8319063) +4 more
core +1 more source
<i>In vitro</i> study on synergistic antifungal effects of docetaxel combined with azoles against dematiaceous fungi and <i>Aspergillus niger</i>. [PDF]
Front MicrobiolBackground Dematiaceous fungal infections are frequently encountered in clinical practice with no unified treatment.
Zhang H +7 more
europepmc +2 more sources