Results 81 to 90 of about 1,302,226 (351)

Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age‐ and BMI‐Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler, Aleksandra Maleska Maceski, Sofia Sandgren, Johanna Oechtering, Sabine Schaedelin, Lisa Hofer, Amar Zadic, Juan Francisco Vilchez Gomez, Lester Melie‐Garcia, Alessandro Cagol, Riccardo Galbusera, Sebastian Finkener, Patrice Lalive, Marjolaine Uginet, Stefanie Müller, Caroline Pot, Amandine Mathias, Renaud Du Pasquier, Robert Hoepner, Andrew Chan, Giulio Disanto, Chiara Zecca, Marcus D’Souza, Lars G. Hemkens, Tobias Derfuss, Özgür Yaldizli, Patrick Roth, Claudio Gobbi, David Brassat, Björn Tackenberg, Henrik Zetterberg, Tjalf Ziemssen, Heinz Wiendl, Klaus Berger, Marco Hermesdorf, Fredrik Piehl, Ludwig Kappos, Cristina Granziera, Ahmed Abdelhak, David Leppert, Eline A. J. Willemse, Pascal Benkert, Jens Kuhle, Swiss Multiple Sclerosis Cohort Study (SMSC)   +43 more
wiley   +1 more source

Risk factors for dementia in the ninth decade of life and beyond: a study of the Lothian birth cohort 1921

BMC Psychiatry, 2017
Background With increasing numbers of people surviving beyond eighty years, this section of the population demands attention to reduce the impact of dementia.
Ruth A. Sibbett, Tom C. Russ, Ian J. Deary, John M. Starr   +3 more
doaj   +1 more source

End-of-life care and dementia [PDF]

, 2006
In the UK, research continues to confirm that people with certain chronic illnesses, such as chronic lung disease and cardiac failure, represent the ‘disadvantaged dying’ compared to those with terminal cancer.
Ballard, Clive, Daley, Sarah, Hughes, Julian, Keady, John, Robinson, Louise, Volicer, Ladislav   +5 more
core   +1 more source

Awareness, requirements and barriers to use of Assistive Technology designed to enable independence of people suffering from Dementia (ATD) [PDF]

, 2012
This article is available through the Brunel Open Access Publishing Fund. Copyright @ 2012 IOS PressThis study investigated the awareness and use of assistive technology for people with dementia. The aim of the study was to explore barriers to the uptake
Jowitt, F, McIntyre, A, van den Heuvel, EA   +2 more
core   +1 more source

Association of Lifestyle and Genetic Risk With Incidence of Dementia.

Journal of the American Medical Association (JAMA), 2019
Importance Genetic factors increase risk of dementia, but the extent to which this can be offset by lifestyle factors is unknown. Objective To investigate whether a healthy lifestyle is associated with lower risk of dementia regardless of genetic risk.
Ilianna Lourida, E. Hannon, T. Littlejohns, K. Langa, E. Hyppönen, E. Kuźma, D. Llewellyn   +6 more
semanticscholar   +1 more source

Ageism in Rheumatology: The Health Care Professional's Perspective

Arthritis Care &Research, EarlyView.
Objective Ageism (age‐based stereotypes, prejudice, or discrimination) is prevalent and linked to prolonged disability and reduced lifespan in older adults. Little is known about ageism within rheumatology. This study explores the health care professional's (HCP) perception of the care of older adults and how ageist attitudes or perspectives may impact
Aaron P. Smith, Pooja M. Achanta, Jiha Lee, Namrata Singh, Una E. Makris   +4 more
wiley   +1 more source

The brain basis of musicophilia: evidence from frontotemporal lobar degeneration

Frontiers in Psychology, 2013
Musicophilia, or abnormal craving for music, is a poorly understood phenomenon that has been associated in particular with focal degeneration of the temporal lobes.
Phillip David Fletcher, Laura eDowney, Pirada eWitoonpanich, Jason eWarren   +3 more
doaj   +1 more source

The effect of COVID-19 on the home behaviours of people affected by dementia

npj Digital Medicine, 2022
The COVID-19 pandemic has dramatically altered the behaviour of most of the world’s population, particularly affecting the elderly, including people living with dementia (PLwD). Here we use remote home monitoring technology deployed into 31 homes of PLwD
Alina-Irina Serban, Eyal Soreq, Payam Barnaghi, Sarah Daniels, Rafael A. Calvo, CR&T Group, David J. Sharp   +6 more
doaj   +1 more source

Cornell Scale for Depression in Dementia

International Psychogeriatrics, 1997
BESKRIVELSE Baggrunden for udviklingen af CSDD var, at de fleste andre in­ strumenter til vurdering af depression er baseret på patientens egne oplysninger via spørgeskema eller interview, hvilket er en mindre pålidelig metode, hvis patienten pga. demens

semanticscholar   +1 more source

Serum uric acid levels in older adults: Associations with clinical outcomes and implications for reference intervals in those aged 70 years and over

Arthritis Care &Research, Accepted Article.
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard, Cammie Tran, Hans G Schneider, Flavia M Cicuttini, Anita E Wluka, Ego Seeman, Johannes T Neumann, Md Nazmul Karim, Zhen Zhou, Sultana Monira Hussain, David P Q Clark, Daniel Clayton‐Chubb, Andrew M Tonkin, Lawrence J Beilin, Robyn L Woods, John J McNeil   +15 more
wiley   +1 more source