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Higher molecular weight alpha-synuclein oligomers are increased in brain cytosol from dementia with Lewy bodies

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Gregersen E   +6 more
europepmc   +1 more source
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Dementia with Lewy bodies

The Lancet Neurology, 2004
Dementia with Lewy bodies (DLB) is the second commonest cause of neurodegenerative dementia in older people. It is part of the range of clinical presentations that share a neuritic pathology based on abnormal aggregation of the synaptic protein alpha-synuclein.
Ian, McKeith   +18 more
  +8 more sources

Dementia with Lewy Bodies

Science of Aging Knowledge Environment, 2001
In this case study, we describe the symptoms, neuropsychological testing, and brain pathology of a man with dementia with Lewy bodies. Dementia with Lewy bodies might be the second most common form of degenerative dementia in the elderly. Progressive cognitive decline, well-formed visual hallucinations, and parkinsonism are core features of this ...
H, Posner, S, Chin, K, Marder
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Dementia with Lewy bodies

Journal of the Neurological Sciences, 2006
Advanced Parkinson's disease (PD) is frequently associated with dementia. The pathogenesis of this dementia is complex, related to deficiency of several biogenic amines and cortical Lewy body deposition, as well as co-existent age-related brain changes, both of the Alzheimer type and vascular.
Amos D, Korczyn, Heinz, Reichmann
openaire   +2 more sources

Dementia with Lewy bodies

Current Opinion in Neurology, 1996
Dementia with Lewy bodies is a generic term which was proposed at the first International Workshop on Lewy Body Dementia (Newcastle upon Tyne, 1995). It is an all encompassing term that includes various types of disorder such as diffuse Lewy body disease, senile dementia of Lewy body type, and Lewy body variant of Alzheimer's disease.
K, Kosaka, E, Iseki
openaire   +2 more sources

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