Kwaliteit van leven bij dementie [PDF]
In de literatuur worden verschillende definities van ‘kwaliteit van leven’ gevonden. Dit roept de vraag op welke domeinen als belangrijk worden gezien door mensen met dementie zelf.
D. L. Gerritsen +8 more
doaj +2 more sources
Advance Care Planning Among People With Dementia in the Netherlands: Insights From an Exploratory Survey of Health Care Professional Perspectives. [PDF]
ABSTRACT Background Advance care planning (ACP) for patients with dementia has gained increasing attention in recent years, recognizing the importance of aligning future care with the values and preferences of patients with progressive cognitive decline. Health care professionals (HCPs) play an important role in facilitating ACP.
Vandaele LL +7 more
europepmc +2 more sources
Biomarker-Based Diagnosis and Care Pathways for Alzheimer's Disease in the Era of Disease-Modifying Treatments: A Consensus Statement by Belgian Experts. [PDF]
ABSTRACT Background The recent approval of disease‐modifying therapies (DMTs) for early Alzheimer's disease (AD) marks a major shift in clinical practice. Biomarker confirmation of amyloid pathology is now required alongside clinical assessment, and blood‐based tests are improving accessibility.
Van Langenhove T +31 more
europepmc +2 more sources
"Real-world" eligibility for anti-amyloid treatment in a tertiary memory clinic setting. [PDF]
Abstract INTRODUCTION The societal impact of anti‐amyloid treatment (AAT) for Alzheimer's disease (AD) depends largely on patient eligibility. Estimates suggest that 1% to 18% of individuals with AD may qualify for AAT; however, data from everyday clinical practice remain limited.
Vigneswaran S +8 more
europepmc +2 more sources
Structural and functional connectivity in tau mutation carriers: from presymptomatic to symptomatic frontotemporal dementia. [PDF]
Abstract INTRODUCTION Microtubule‐associated protein tau (MAPT) mutations cause frontotemporal dementia (FTD), characterised by behavioural, language, and motor impairments due to brain connectivity disruptions. We investigated structural and functional connectivity in 86 mutation carriers and 272 controls to map connectivity changes at different ...
Bouzigues A +38 more
europepmc +2 more sources
Cross-country variance in facial emotion recognition in presymptomatic and symptomatic behavioral variant frontotemporal dementia: Insights from the GENFI and ReDLat consortia. [PDF]
Abstract INTRODUCTION We investigated international differences in facial emotion recognition (FER) across stages of frontotemporal dementia (FTD). Previous studies may have missed early decline by combining data and masking variations in FER across countries.
de Boer L +45 more
europepmc +2 more sources
Sex differences in clinical phenotypes of behavioral variant frontotemporal dementia. [PDF]
Abstract INTRODUCTION Higher male prevalence in sporadic behavioral variant frontotemporal dementia (bvFTD) has been reported. We hypothesized differences in phenotypes between genetic and sporadic bvFTD females resulting in underdiagnosis of sporadic bvFTD females.
Liu X +74 more
europepmc +2 more sources
Door de dubbele vergrijzing (meer ouderen leven langer) zal het aantal mensen met dementie de komende jaren sterk toenemen. Dementie is een overkoepelend verzamelbegrip met vele verschillende oorzaken.
Hobbelen, Johannes, Verhey, Frans
core +1 more source
De Amsterdamse Dementie-Screeningstest (ADS) bestaat uit zes subtests voor onderzoek van leren en geheugen (Visueel geheugen, Oriëntatie, Achtwoordentest), executieve functies (Meander), taal (Fluency) en visueel-constructievermogen (Natekenen).
Meta van Toutert +2 more
doaj +1 more source
Biomarkers of endothelial dysfunction and cognition: A two-step IPD meta-analysis. [PDF]
Abstract INTRODUCTION This study assessed the association of plasma biomarkers of endothelial dysfunction with cognitive performance and decline. METHODS Data from 9414 individuals from eight Dutch cohorts were included (Ø age‐range: 57–93 years). Plasma biomarkers of endothelial dysfunction (soluble intercellular adhesion molecule‐1 (sICAM‐1), soluble
Beran M +23 more
europepmc +2 more sources

