Advance Care Planning Among People With Dementia in the Netherlands: Insights From an Exploratory Survey of Health Care Professional Perspectives. [PDF]
ABSTRACT Background Advance care planning (ACP) for patients with dementia has gained increasing attention in recent years, recognizing the importance of aligning future care with the values and preferences of patients with progressive cognitive decline. Health care professionals (HCPs) play an important role in facilitating ACP.
Vandaele LL +7 more
europepmc +2 more sources
"Real-world" eligibility for anti-amyloid treatment in a tertiary memory clinic setting. [PDF]
Abstract INTRODUCTION The societal impact of anti‐amyloid treatment (AAT) for Alzheimer's disease (AD) depends largely on patient eligibility. Estimates suggest that 1% to 18% of individuals with AD may qualify for AAT; however, data from everyday clinical practice remain limited.
Vigneswaran S +8 more
europepmc +2 more sources
Structural and functional connectivity in tau mutation carriers: from presymptomatic to symptomatic frontotemporal dementia. [PDF]
Abstract INTRODUCTION Microtubule‐associated protein tau (MAPT) mutations cause frontotemporal dementia (FTD), characterised by behavioural, language, and motor impairments due to brain connectivity disruptions. We investigated structural and functional connectivity in 86 mutation carriers and 272 controls to map connectivity changes at different ...
Bouzigues A +38 more
europepmc +2 more sources
Cross-country variance in facial emotion recognition in presymptomatic and symptomatic behavioral variant frontotemporal dementia: Insights from the GENFI and ReDLat consortia. [PDF]
Abstract INTRODUCTION We investigated international differences in facial emotion recognition (FER) across stages of frontotemporal dementia (FTD). Previous studies may have missed early decline by combining data and masking variations in FER across countries.
de Boer L +45 more
europepmc +2 more sources
Sex differences in clinical phenotypes of behavioral variant frontotemporal dementia. [PDF]
Abstract INTRODUCTION Higher male prevalence in sporadic behavioral variant frontotemporal dementia (bvFTD) has been reported. We hypothesized differences in phenotypes between genetic and sporadic bvFTD females resulting in underdiagnosis of sporadic bvFTD females.
Liu X +74 more
europepmc +2 more sources
Distinctive cell-free DNA methylation characterizes presymptomatic genetic frontotemporal dementia. [PDF]
Abstract Objective Methylation of plasma cell‐free DNA (cfDNA) has potential as a marker of brain damage in neurodegenerative diseases such as frontotemporal dementia (FTD). Here, we study methylation of cfDNA in presymptomatic and symptomatic carriers of genetic FTD pathogenic variants, next to healthy controls.
Giannini LAA +14 more
europepmc +2 more sources
Biomarkers of endothelial dysfunction and cognition: A two-step IPD meta-analysis. [PDF]
Abstract INTRODUCTION This study assessed the association of plasma biomarkers of endothelial dysfunction with cognitive performance and decline. METHODS Data from 9414 individuals from eight Dutch cohorts were included (Ø age‐range: 57–93 years). Plasma biomarkers of endothelial dysfunction (soluble intercellular adhesion molecule‐1 (sICAM‐1), soluble
Beran M +23 more
europepmc +2 more sources
Casemanagers over hun rol bij (toekomstige) euthanasiewensen van mensen met dementie
Om te anticiperen op mogelijk toekomstig lijden als gevolg van dementie stellen mensen steeds vaker een schriftelijke euthanasieverklaring op. In de praktijk is euthanasie bij mensen met gevorderde dementie en een schriftelijke euthanasieverklaring ...
Marjolijn A. van Daalen +3 more
doaj +1 more source
Psychologen en openheid over de diagnose dementie aan de patiënt: een verkennend onderzoek
Doel In deze verkennende studie naar openheid onder psychologen over de diagnose dementie staan de volgende vragen centraal. Welke opvattingen hebben psychologen over openheid inzake de diagnose dementie? Wat zeggen ze feitelijk tegen patiënten?
M. Kootte, N. Steverink
doaj +1 more source
Vooruitdenken – Steun voor naasten van verpleeghuisbewoners met dementie in proactieve zorgplanning
Dementie is een ongeneeslijke ziekte. Daarom is een zorgaanpak nodig die zich richt op de kwaliteit van leven van mensen met dementie en hun naasten: palliatieve zorg. In deze zorg is het belangrijk om vooruit te denken over wensen en grenzen in de zorg
Laura Bavelaar
doaj

