Results 171 to 180 of about 77,623 (261)

Demo video of Schrödinger\u27s box: "trash can"

Demo video of Schrödinger\u27s box: "trash ...
Weger, Marian (University of Music and Performing Arts Graz, Austria)
core  

HDGNN-Mamba2: Mamba-Based Spatiotemporal Heterogeneous Dynamic Graph Neural Network for Major Depressive Disorder Classification. [PDF]

Brain Sci
Yan J, Gui R, Liang H, Wang Y.
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Demo video of Schrödinger\u27s box: "big metal thing"

Demo video of Schrödinger\u27s box: "big metal ...
Weger, Marian (University of Music and Performing Arts Graz, Austria)
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Demo video of Schrödinger\u27s box: "glass break"

Demo video of Schrödinger\u27s box: "glass ...
Weger, Marian (University of Music and Performing Arts Graz, Austria)
core  

ViroBioTree: A Tree-Structured Biological Evidence Retrieval Framework for Viral Protein Function Annotation. [PDF]

Viruses
Lai T, Liu F, Li G, Hua L.
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Demo video of Schrödinger\u27s box: "metal handrail"

Demo video of Schrödinger\u27s box: "metal ...
Weger, Marian (University of Music and Performing Arts Graz, Austria)
core  

HealthFlow: automating electronic health record analysis via a strategically self-evolving multi-agent framework. [PDF]

NPJ Digit Med
Zhu Y, Wang Z, Qi Y, Gu L, Sui D, Hu H, Zhang X, He Z, Wang Y, He J, Ma L, Yu L.   +11 more
europepmc   +1 more source