Results 231 to 240 of about 77,623 (261)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Trustworthy and ethical intrusion detection for healthcare internet of medical things using reinforcement learning and governance rules. [PDF]

Sci Rep
Adabara I, Sadiq BO, Shuaibu AN, Danjuma YI, Maninti V, Joe M.   +5 more
europepmc   +1 more source

Visualization and simulation of full-scale point-neuron circuits via the Neural Circuit Visualizer web platform. [PDF]

Sci Rep
Ali M, Smiriglia R, Spera E, Mirani SA, Solinas SMG, Migliore M, Ascoli GA, Bologna LL.   +7 more
europepmc   +1 more source

Correction for Yuan et al., Oil-water interfaces drive gold precipitation via microdroplet chemistry in thermal geological systems. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Social evaluation of skilfulness in Tonkean macaques (Macaca tonkeana) and brown capuchins (Sapajus apella). [PDF]

Anim Cogn
Hirel M, Marziliano M, Meunier H, Rakoczy H, Fischer J, Keupp S.   +5 more
europepmc   +1 more source

Simulating the landscape eco-evolution of host-pathogen systems with CDMetaPOP.

Ecol Inform
Landguth EL, Williams A, Roseman M, Amadi M, Fain B, Kouete M, Farrer RA, Haeseler AJ, Razgour O, Richardson C, Weckworth B, Weckworth J, Whiting-Fawcett F, Wilson D, Day CC.   +14 more
europepmc   +1 more source

Drug-induced Aseptic Meningitis: Pharmacovigilance Analysis of Japanese Adverse Event Reporting Database. [PDF]

In Vivo
Masago S, Kotake K, Yamaoka K, Yorifuji K, Shimizu T.   +4 more
europepmc   +1 more source

From Device-Level Implementation to In-Sensor Computing in Memristive-Device-Based Biosensors: A Review. [PDF]

Biosensors (Basel)
Ryu H, Lee WC, Lee J.
europepmc   +1 more source