Results 31 to 40 of about 43,512 (267)
Hidden order across online extremist movements can be disrupted by nudging collective chemistry
Scientific Reports, 2021 Disrupting the emergence and evolution of potentially violent online extremist movements is a crucial challenge. Extremism research has analyzed such movements in detail, focusing on individual- and movement-level characteristics.
N. Velásquez +7 more
doaj +1 more source
Physical Review D, 2019 We conjecture that there exists a scalar bound state for every pair of fundamental fermions at a UV (`composite') scale, $ \gg v_{\text{weak}}$. This implies a large number of universally coupled, sub-critical Higgs doublets. All but the Standard Model Higgs are `dormant,' with large positive squared masses and each receives a small vacuum expectation
Hill, Christopher T. +3 more
openaire +3 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The Pain of Modern Life: The Misery of Modern Existence
Research on Ageing and Social PolicySocial isolation and loneliness are posing more problems than ever. There are concerns that the long-term effects of loneliness will be felt when the COVID-19 outbreak reaches its third year.
Meltem Ince Yenilmez +1 more
doaj +1 more source
Deflating the Chinese balloon: types of Twitter bots in US-China balloon incident
EPJ Data Science, 2023 As digitalization increases, countries employ digital diplomacy, harnessing digital resources to project their desired image. Digital diplomacy also encompasses the interactivity of digital platforms, providing a trove of public opinion that diplomatic ...
Lynnette Hui Xian Ng, Kathleen M. Carley
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The Mysterious Travel of Drugs from Nature to Pharmacy
Forbes Tıp DergisiFor thousands of years, people have used various substances found in nature to relieve symptoms and even cure diseases. Drugs are medicinal products obtained from natural sources such as plants, animals, and microorganisms or synthesized in the ...
Gülden DİNİZ +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Examining Preschool Children's Mathematical Experiences with Loose Parts
Uluslararası Türk Eğitim Bilimleri DergisiStudies on loose parts have predominantly focused on their use in outdoor environments, while research on the use of loose parts indoors has been found to be limited.
İrem Köleoğlu, İrem Gürgah Oğul
doaj +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source