Results 61 to 70 of about 1,477,829 (339)

Is democracy promotion effective in Moldova? The impact of European institutions on development of civil and political rights in Moldova [PDF]

open access: yes, 2008
The main focus of this study is an analysis of the impact on civil and political rights of democracy promotion strategies applied by the three European organizations in Moldova in the 1990s-early 2000s.
McDonagh, Ecaterina
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

The Pain of Modern Life: The Misery of Modern Existence

open access: yesResearch on Ageing and Social Policy
Social isolation and loneliness are posing more problems than ever. There are concerns that the long-term effects of loneliness will be felt when the COVID-19 outbreak reaches its third year.
Meltem Ince Yenilmez   +1 more
doaj   +1 more source

Democracy of Objects [PDF]

open access: yes, 2011
In The Democracy of Objects Bryant proposes that we break with the epistemological tradition and once again initiate the project of ontology as first philosophy. Bryant develops a realist ontology, called -onticology-, which argues that being is composed entirely of objects, properties, and relations.
openaire   +5 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

The Mysterious Travel of Drugs from Nature to Pharmacy

open access: yesForbes Tıp Dergisi
For thousands of years, people have used various substances found in nature to relieve symptoms and even cure diseases. Drugs are medicinal products obtained from natural sources such as plants, animals, and microorganisms or synthesized in the ...
Gülden DİNİZ   +5 more
doaj   +1 more source

THE PROBLEM OF ACADEMIC GENDER MOBBING IN TURKISH UNIVERSITIES

open access: yesRevista de Investigaciones Universidad del Quindío, 2021
The issue of academic mobbing is growing at an alarming rate in Turkish universities. This is a negative practice whereby outspoken and ethical scholars are attacked. These scholars are always kicking against bad practices in society.
Meltem Ince-Yenilmez
doaj   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Democracy: Concepts, Measures and Relationships [PDF]

open access: yes, 2011
This briefing paper reviews the existing research and debates on the causes and consequences of democracy to provide guidance on the key conceptual and methodological issues surrounding democracy promotion and aid conditionality.
Landman, T
core  

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

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