Results 61 to 70 of about 540,720 (359)

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

The Mysterious Travel of Drugs from Nature to Pharmacy

Forbes Tıp Dergisi
For thousands of years, people have used various substances found in nature to relieve symptoms and even cure diseases. Drugs are medicinal products obtained from natural sources such as plants, animals, and microorganisms or synthesized in the ...
Gülden DİNİZ, Şervan VEYSANOĞLU, Simge İNAL, Buket ARAÇ, Neslihan Düzenli, Emine Müge KARAKAYALI   +5 more
doaj   +1 more source

Pandora's Ballot Box: Electoral Politics of Direct Democracy [PDF]

arXiv, 2022
We study how office-seeking parties use direct democracy to shape elections. A party with a strong electoral base can benefit from using a binding referendum to resolve issues that divide its core supporters. When referendums do not bind, however, an electorally disadvantaged party may initiate a referendum to elevate new issues in order to divide the ...
arxiv  

Democracy of Objects [PDF]

, 2011
In The Democracy of Objects Bryant proposes that we break with the epistemological tradition and once again initiate the project of ontology as first philosophy. Bryant develops a realist ontology, called -onticology-, which argues that being is composed entirely of objects, properties, and relations.
openaire   +5 more sources

Log file‐based quality assurance method for respiratory gating system

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background As medical linear accelerator technology advances, enabling higher dose rate deliveries, hypofractionation regimens has increased. This necessitates respiratory gating systems that synchronize radiation delivery with tumor position, requiring simple rigorous quality assurance (QA) to ensure treatment accuracy and patient safety ...
Wonjoong Cheon, Young Kyu Lee, Yunji Seol, Chan‐beom Park, Hong Qi Tan, Kyu Hye Choi, Young‐nam Kang, Byung Ock Choi   +7 more
wiley   +1 more source

The Pain of Modern Life: The Misery of Modern Existence

Research on Ageing and Social Policy
Social isolation and loneliness are posing more problems than ever. There are concerns that the long-term effects of loneliness will be felt when the COVID-19 outbreak reaches its third year.
Meltem Ince Yenilmez, Eylül Kabakçı Günay   +1 more
doaj   +1 more source

Evaluating feature extraction reproducibility across image biomarker standardization initiative‐compliant radiomics platforms using a digital phantom

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The aim of this study was to thoroughly analyze the reproducibility of radiomics feature extraction across three Image Biomarker Standardization Initiative (IBSI)‐compliant platforms using a digital phantom for benchmarking. It uncovers high consistency among common features while also pointing out the necessity for standardization ...
Han‐Back Shin, Heesoon Sheen, Jang‐Hoon Oh, Young Eun Choi, Kihoon Sung, Hyun Ju Kim   +5 more
wiley   +1 more source

Flavor Democracy in Particle Physics [PDF]

AIPConf.Proc.899:49-52,2007, 2006
The flavor democracy hypothesis was introduced in seventies taking in mind three Standard Model (SM) families. Later, this idea was disfavored by the large value of the t-quark mass. In nineties the hypothesis was revisited assuming that extra SM families exist.
arxiv   +1 more source

Pregnancy Outcomes of Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Among Patients With Autoimmune Diseases: A Scoping Review

Arthritis Care &Research, EarlyView.
Objective Targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) have expanded the management of autoimmune diseases, including rheumatic diseases. As the use of these drugs grows, it is important to understand their effects on pregnancy.
Vienna Cheng, Neda Amiri, Vicki Cheng, Ursula Ellis, Jacquelyn J. Cragg, Mark Harrison, Laurie Proulx, Mary A. De Vera   +7 more
wiley   +1 more source

Comparative Wear and Friction Analysis of Sliding Surface Materials for Hydrostatic Bearing under Oil Supply Failure Conditions

Advanced Engineering Materials, EarlyView.
Hydrostatic bearings excel in high‐precision applications, but their performance hinges on a continuous external supply. This study evaluates various material combinations for sliding surfaces to mitigate damage during supply failures or misalignment and to discover the most effective materials identified for enhancing the reliability and efficiency of
Michal Michalec, Lukáš Daněk, Jan Foltýn, Petr Svoboda, Carsten Gachot, Martin Hartl, Ivan Křupka   +6 more
wiley   +1 more source