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Lotilaner (Xdemvy) for Demodex Blepharitis

The Medical Letter on Drugs and Therapeutics
The FDA has approved a 0.25% ophthalmic solution of the ectoparasiticide lotilaner (Xdemvy – Tarsus) for treatment of Demodex blepharitis. Lotilaner is the first drug to be approved in the US for this indication.
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Traditional and Novel Treatment of Demodex Blepharitis

Journal of Medical Optometry
A 77-year-old male presented for a dry eye evaluation with symptoms of irritation that started in the right eye and then the left eye for at least four days...
Gulnoza Azieva Gomez   +2 more
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Update on the Management of Demodex Blepharitis

Cornea, 2021
Abstract: Demodex blepharitis is a common ophthalmologic disease that is often overlooked in the workup of blepharitis. Demodex infestation occurs in both symptomatic and asymptomatic individuals at similar rates; consequently, its role in the development of blepharitis has not been well elucidated.
Paras P. Shah   +2 more
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Demodex Folliculorum and Blepharitis

Archives of Dermatology, 1963
For many years Demodex folliculorum has been recognized as an inhabitant of the pores of the skin, particularly in the face. Except for a detailed study by Stcherbatchoff in 1903, only casual reference has been made to its presence in the eyelid structures of man.
C F, POST, E, JUHLIN
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DEMODEX BLEPHARITIS- AN UNDER-RECOGNIZED DIAGNOSIS

Annals of Allergy, Asthma & Immunology
D. Garcia De Guzman   +2 more
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Meibomian gland structure and function in patients with Demodex blepharitis

Journal of cataract and refractive surgery
In eyes with moderate to severe Demodex blepharitis (collarette grades 2 to 4), the meibum quality, telangiectasia score, and MG atrophy were significantly worse than those with collarette grade 0.
Elizabeth Yeu, Cecelia Koetting
semanticscholar   +1 more source

Is Demodex Blepharitis Connected With Cataract Surgery?

American Journal of Ophthalmology, 2023
To determine whether there is an increased incidence of Demodex of the eyelashes among patients after cataract extraction surgery.Prospective, noncomparative clinical study.A cohort of patients who underwent cataract extraction surgery had several eyelashes removed preoperatively that were examined independently by the hospital laboratory for the ...
Ilan Feldman   +7 more
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Lotilaner for Demodex Blepharitis: The Journey from Veterinary Use to Human Medicine

Journal of Ocular Pharmacology and Therapeutics
In 2023, Xdemvy® (0.25% lotilaner ophthalmic solution) was approved by the U.S. FDA for treating Demodex blepharitis in humans. This article reviews lotilaner’s history, physicochemical properties, pharmacokinetics, pharmacology, clinical outcomes, and ...
Akanksha Sharma   +2 more
semanticscholar   +1 more source

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