Results 61 to 70 of about 3,614,818 (309)

Exploring oral cancer patterns: A 5-year retrospective analysis of incidence, clinical features, patient behaviour and treatment outcomes at the dental unit of a private medical college and hospital in Varanasi, Uttar Pradesh

Advances in Human Biology
Introduction: Oral cancer is a global health challenge. In India, there is a huge burden on the healthcare system. The prevalence of oral cancer globally and in India, coupled with the specific risk factors associated with the Indian population ...
Ravi Kumar, Aparajita Tiwari, Vishal Singh   +2 more
doaj   +1 more source

Effects of reproductive and demographic changes on breast cancer incidence in China: A modeling analysis [PDF]

, 2008
Background: Breast cancer incidence is currently low in China. However, the distribution of reproductive and lifestyle risk factors for breast cancer among Chinese women is changing rapidly.
Colditz, Graham A., Gao, Yu-Tang, Hesketh, Therese, Linos, Eleni, Linos, Katerina, Qu, Jian Ding, Rosner, Bernard A., Spanos, Demetri, Zheng, Wei   +8 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Efficacy of Pharmacological Treatments in Managing Generalized Anxiety Disorder among Adults in Saudi Arabia: A Cross-sectional Analysis

Dr. Sulaiman Al Habib Medical Journal
Introduction: Generalized anxiety disorder (GAD) is a significant mental health concern characterized by excessive and uncontrollable worry about everyday activities.
Abdulsalam Mohammed Aleid, Abdulaziz Matar Alharthi, Rana Abdulmohsen Alotaibi, Ahmed Mohammed Alasmari, Sharifah Ahmed Alzabdawi, Imtinan Jafar Asaeed, Sarah Mousa Alshuqayfi, Shuruq Mohammed Alzahuf, Aliyah Matar Alharthi, Mostafa Habeeb Alhodibi   +9 more
doaj   +1 more source

Demographic Analysis of Birthweight-Specific Neonatal Mortality [PDF]

This paper explores the determinants of birthweight-specific neonatal mortality rates across States in the U.S. in 1980. We are able to explore the interactions between the determinants and birthweight because of the new data available through the ...
Hope Corman, Michael Grossman, Theodore J. Joyce   +2 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

CANONICAL CORRELATION ANALYSIS OF SELECTED DEMOGRAPHIC AND HEALTH PERSONNEL VARIABLES [PDF]

Labor and Human Capital,
Doeksen, Gerald A., Dunn, James W.
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source