Results 71 to 80 of about 2,723,782 (316)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Environmental Research LettersIt is anticipated that climate change and climate variability will threaten food and nutrition security through multiple pathways, yet evidence on its impact on minimum dietary diversity for women (MDD-W), especially in low- and middle- income countries (
B Carducci +9 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Metropolitan Development Policies and Demographic. Dynamics in Sicily [PDF]
This article will take in consideration the co-existence in Sicily of different models of urbanisation with rising complex problems. Particularly we notice: A) in the coastal conurbations with infrastructural improvements, there is a timid ...
Luigi Scrofani, Vittorio Ruggiero
core
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
DEMOGRAPHIC, SOCIAL, ECONOMIC AND GEOGRAPHIC FEATURES – SHAPING FACTORS OF THE TOURIST MARKET [PDF]
One of the major themes which have more and more importance at a European level, but also at a national level, is the demographic evolution and its effects in the different fields of the social and economic life.
Mirela Mazilu, Sabina Mitroi
core
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
A comparison of demographic behaviour between the CR regions using multivariate statistical methods
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2008 The inhabitants of separate CR regions show varying demographic behaviour that presents itself in the demographic measures´ values. The paper offers a comparison of the development of selected measures of size and movement of the population in the ...
Marie Prášilová +2 more
doaj +1 more source