Results 111 to 120 of about 16,705,613 (340)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Factors Related to Evidence-Based Practices Among Mental Health Nurses in Thailand: A Cross-Sectional Study

Nursing Reports
Background and Objectives: Despite the robustness of evidence-based practice in increasing efficiency in nursing care and improving patient safety, using evidence in practice is still rare in mental health nursing. This correlational descriptive research
Napapat Manitkul, Kwaunpanomporn Thummathai, Patraporn Bhatarasakoon   +2 more
doaj   +1 more source

Klasyfikacja podregionów przygranicznych Polski Wschodniej według poziomu rozwoju społeczno-gospodarczego

Polityki Europejskie, Finanse i Marketing, 2019
W artykule przeprowadzono klasyfikację podregionów (NUTS 3), na obszarze których znajdowały się stałe przejścia graniczne, pod względem poziomu rozwoju społeczno-gospodarczego.
Iwona Pomianek
doaj   +1 more source

Effects of demographic factors on technological change and economic growth [PDF]

The endogenous technology literature usually treats human capital as proportional to the population level. As a result, it finds a linear relationship between the population size or growth rate and technological improvement.
Misoulis, Nicholas
core  

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

An Analysis of the Variables Influencing Consumers' Purchasing Decisions for Organic Food Items in Rajkot

International Journal of Emerging Research in Engineering, Science, and Management
This study explores the key factors influencing consumer behavior in the organic food market of Rajkot City. Empirical research reveals that price is the most significant determinant across demographic groups, strongly influenced by age, education ...
Thakrar Pooja Tulshibhai, N. D. Zala
doaj   +1 more source

U.S. Variations in Child Health System Performance: A State Scorecard [PDF]

, 2008
Ranks state child health systems on thirteen measurements of five dimensions: access, quality, costs, equity, and potential to lead healthy lives.
Edward L. Schor, Karen Davis, Katherine K. Shea   +2 more
core  

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source