Results 71 to 80 of about 3,216,066 (314)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Demographic Influences on Sustainable Mobility Adoption in Rehabilitation

Surabaya Physical Medicine and Rehabilitation Journal
Background: The integration of sustainable mobility within rehabilitation settings combines environmental and health-focused strategies to reduce the carbon footprint of healthcare and improve patient results.
Denis Arsovski, Viktorija Prodanovska-Stojchevska, Tanja Jovanovska, Izabela Filov, Angelka Jankulovska, Daniela Petkovska   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Forecasting Youth Unemployment Through Educational and Demographic Indicators: A Panel Time-Series Approach

Forecasting
Youth unemployment remains a pressing issue in many emerging economies, where educational disparities and demographic pressures interact in complex ways.
Arsen Tleppayev, Saule Zeinolla
doaj   +1 more source

Lessons From High- and Low-Performing States for Raising Overall Health System Performance [PDF]

, 2011
Examines socioeconomic, demographic, political, cultural, and marketplace factors that influence health system improvement in high- and low-ranking states in the State Scorecard on Health System Performance and outlines promising ...
Greg Moody, Sharon Silow-Carroll
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Identification of Demographic Factors Affecting Student Performance using Tree-Based Machine Learning Models

JTAM (Jurnal Teori dan Aplikasi Matematika)
This study aims to identify key academic and demographic factors influencing student performance in the Logic and Set Theory course, particularly in the context of different learning modes during and after the COVID-19 pandemic.
Chatarina Enny Murwaningtyas
doaj   +1 more source

THE PROFESSIONAL ACTIVITIES OF PERSONS WITH PHYSICAL DISABILITIES FROM LUBLIN PROVINCE IN THE LIGHT OF SOCIAL AND DEMOGRAPHIC FACTORS

Rozprawy Społeczne, 2019
Introduction The level of involvement in economic activity of people with disabilities is influenced by various demographic factors. The objective of the work was an evaluation of the professional activities of persons with physical disabilities who were
Grzegorz Józef Nowicki, Magdalena Młynarska, Jolanta Dyndur, Barbara Ślusarska, Jacek Jagnicki, Ewa Chemperek   +5 more
doaj   +1 more source

Has the "Farm Problem" Disappeared? A Comparison of Household and Self-Employment Income Levels of the Farm and Nonfarm Self-Employed [PDF]

This study tests the impact of household and demographic factors on the economic well-being of the farm and nonfarm self-employed using data from the Integrated Public Use Microdata Series.
Marshall, Maria I., Peake, Whitney O.
core   +1 more source

KIDS COUNT Indicator Brief: Preventing Low Birthweight [PDF]

, 2009
Outlines trends in low birthweight and preterm births and offers prevention strategies such as expanding access to comprehensive health care, ensuring good nutrition for pregnant women, and addressing demographic, social, and environmental risk ...
Barbara Shore, Rima Shore
core