Results 221 to 230 of about 1,891,311 (301)

Molecular features of human pathological tau distinguish tauopathy-associated dementias. [PDF]

Cell
Kumar M, Schlaffner CN, Tang S, Beuvink MA, Viode A, Mair W, Jha M, Uncu C, Wesseling H, Wang T, Oakley DH, Beerepoot P, Xue J, Connors TR, Davis DA, Frosch MP, Murray ME, Spina SE, Grinberg LT, Seeley WW, Miller BL, Boxer AL, Geschwind DH, Kosik KS, Dickson DW, Renard BY, DeTure M, McKee AC, Hyman BT, Steen H, Steen JA.   +30 more
europepmc   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Re-identification risk for common privacy preserving patient matching strategies when shared with de-identified demographics. [PDF]

J Am Med Inform Assoc
Eliazar A, Brown JT, Cinamon S, Kantarcioglu M, Malin B.   +4 more
europepmc   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Powering responsible artificial intelligence with high-quality real-world data: the S-RACE platform for scalable, multi-specialty clinical research. [PDF]

NPJ Digit Med
Traverso A, Tiano D, Corvaglia A, Dimonte A, Draetta EL, Fabiani B, Scuri P, Barbieri S, Agazzi M, Arslan M, Celada D, Chiabrando F, Cibrario L, Cielo G, Colombo A, Contini S, Liberotti M, Montagna M, Ogliari FR, Palmisano A, Pisu F, Serra D, Varani D, Vignale D, Vitali AL, Zambello A, Chiapponi C, Denti M, Esposito A, Tacchetti C.   +29 more
europepmc   +1 more source

Dementia Incidence in Individuals With Parkinson's Disease in the Framingham Heart Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Limited information exists on incident dementia in individuals with Parkinson's disease (PD) in US community‐based samples. We examined cognitive statuses and PD diagnoses of 183 individuals in the Framingham Heart Study (FHS) to establish incident dementia, mortality rates, associations with sex, age at PD onset, and education level.
Joshi Dookhy, Michael Cummings, Eden Price, Yulin Liu, Santiago Gutierrez‐Gomez, Sarah O'Shea, Samuel Frank, Rhoda Au, Ashita S. Gurnani, Ting Fang Alvin Ang, Jesse Mez, Ludy C. Shih   +11 more
wiley   +1 more source

Machine learning to predict hospital admission at triage in paediatric emergency care: A meta-analysis. [PDF]

Eur J Pediatr
Pérez BP, Osorio OG, Arias-Colinas M, Moreno JM, Martín-Calvo N.   +4 more
europepmc   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Pre-existing statin use and recurrence in relation to hematoma architecture of chronic subdural hematomas - A propensity score-matched analysis. [PDF]

Brain Spine
Hamou H, Ridwan H, Mausberg A, Fay-Rodrian K, Clusmann H, Hoellig A, Veldeman M.   +6 more
europepmc   +1 more source