Results 1 to 10 of about 384 (124)

Book Chapter in Computational Demography and Health [PDF]

open access: yesarXiv, 2023
Recent developments in computing, data entry and generation, and analytic tools have changed the landscape of modern demography and health research. These changes have come to be known as computational demography, big data, and precision health in the field.
arxiv  

Sociophysics Simulations III: Retirement Demography [PDF]

open access: yes, 2005
This third part of the lecture series deals with the question: Who will pay for your retirement? For Western Europe the answer may be ``nobody'', but for Algeria the demography looks more promising.
arxiv   +1 more source

Supermassive Black-Hole Growth Over Cosmic Time: Active Galaxy Demography, Physics, and Ecology from Chandra Surveys [PDF]

open access: yes, 2010
Extragalactic X-ray surveys over the past decade have dramatically improved understanding of the majority populations of active galactic nuclei (AGNs) over most of the history of the Universe. Here we briefly highlight some of the exciting discoveries about AGN demography, physics, and ecology with a focus on results from Chandra.
arxiv   +1 more source

Detailed kinship estimation for detecting bias among breeding families in a reintroduced population of the endangered bagrid catfish Tachysurus ichikawai

open access: yesPopulation Ecology, Volume 67, Issue 2, Page 109-124, April 2025.
In the process of captive breeding and reintroduction of endangered animal species, it is crucial to minimize familial bias in reproductive success during the reintroduction phase to preserve genetic diversity. In this study, we attempted to identify the familial lineage of individuals of the endangered bagrid fish Tachysurus ichikawai born at the ...
Hinano Mizuno   +5 more
wiley   +1 more source

Comparison of kinship‐identification methods for robust stock assessment using close‐kin mark–recapture data for Pacific bluefin tuna

open access: yesPopulation Ecology, Volume 67, Issue 2, Page 140-152, April 2025.
In this study, we compared three methods for kinship identification using different algorithms in samples of wild Pacific bluefin tuna and generated genotyping data. The three methods resulted in different numbers of inferred kinship pairs for both generated and actual data. Particularly for the half‐sibling pairs, considerable number of false‐positive
Yohei Tsukahara   +5 more
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1422-1435, May 2025.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1117-1131, April 2025.
This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto   +3 more
wiley   +1 more source

The effect of gravitational-wave recoil on the demography of massive black holes [PDF]

open access: yesAstrophys.J. 606 (2004) L17-L20, 2004
The coalescence of massive black hole (MBH) binaries following galaxy mergers is one of the main sources of low-frequency gravitational radiation. A higher-order relativistic phenomenon, the recoil as a result of the non-zero net linear momentum carried away by gravitational waves, may have interesting consequences for the demography of MBHs at the ...
arxiv   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1436-1451, May 2025.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

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