Results 301 to 310 of about 1,763,895 (383)

Trends in formal care by age and time to death: the use of healthcare and care-home facilities in Finland between 2005 and 2018. [PDF]

Eur J Public Health
Dei Bardi L, Moretti M, Cacciani L, Korhonen K, Martikainen P.   +4 more
europepmc   +1 more source

A Dynamic Contrast‐Enhanced MRI‐Based Vision Transformer Model for Distinguishing HER2‐Zero, ‐Low, and ‐Positive Expression in Breast Cancer and Exploring Model Interpretability

Advanced Science, EarlyView.
This study develops a Vision Transformer‐based DCE‐MRI model for the non‐invasive classification of HER2 expression in breast cancer, demonstrating robust performance across multicenter cohorts. By integrating transcriptomic analysis, the model reveals immune‐related pathway differences among distinct HER2 expression levels.
Xu Zhang, Yi‐Yuan Shen, Guan‐Hua Su, Yuan Guo, Ren‐Cheng Zheng, Si‐Yao Du, Si‐Yi Chen, Yi Xiao, Zhi‐Ming Shao, Li‐Na Zhang, He Wang, Yi‐Zhou Jiang, Ya‐Jia Gu, Chao You   +13 more
wiley   +1 more source

Demography Integrated Surveillance for Health Assessment-Geriatric (DISHA-G), a rural cohort of older adults in Odisha, India. [PDF]

Discov Public Health
Kshatri JS, Rehman T, Janssen DJA, Shenkin SD, Palo SK, Pati S.   +5 more
europepmc   +1 more source

Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis

Advanced Science, EarlyView.
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves, Darius Lane, Adam Wahida, Md. Jakaria, Pawel Kalinowski, Adam Southon, Abdel Ali Belaidi, Teresa Samperi‐Esteve, Triet Phu Minh Nguyen, Peng Lei, Marcus Krueger, Stefan Mueller, Marcus Conrad, Puja Agarwal, Sue E Leurgans, Julie Schneider, Ashley I. Bush, Scott Ayton   +17 more
wiley   +1 more source

Constraints to gene flow increase the risk of genome erosion in the Ngorongoro Crater lion population. [PDF]

Commun Biol
Dussex N, Jansson I, van der Valk T, Packer C, Norman A, Kissui BM, E Mjingo E, Spong G.   +7 more
europepmc   +1 more source

The demography of contemporary Polish childhood [PDF]

, 2009
Szukalski, Piotr
core  

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Self-assessed Physical and Mental Health and Fertility Expectations of Men and Women Across the Life Course. [PDF]

Demography
Lazzari E, Beaujouan É.
europepmc   +1 more source

Dedifferentiation and Transfer in Executive Function and Math Ability Following a Five‐Year Abacus Training in Schoolchildren

Advanced Science, EarlyView.
While cognitive development typically exhibits differentiation, marked by decreasing inter‐domain correlations, this study demonstrates that five‐year abacus training is associated with de‐differentiation of executive function and mathematical ability in school‐aged children.
Tianyong Xu, Xinyang Liu, Hongjian He, Changsong Zhou, Andrea Hildebrandt, Feiyan Chen   +5 more
wiley   +1 more source

Comparative Population Genomics Reveal the Determinants of Genome Erosion in Two Sympatric Neotropical Falcons. [PDF]

Mol Ecol
Dussex N.
europepmc   +1 more source