Results 141 to 150 of about 11,230 (258)

Increased self-focus and diminished informativity: referential and structural properties of narrative speech production in borderline personality disorder. [PDF]

Borderline Personal Disord Emot Dysregul
Felletár F, Vincze V, Gosztolya G, Hoffmann I, Babarczy A, Unoka ZS.   +5 more
europepmc   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Cardia-AI: Passive Cardiac Event Monitoring Using Smartwatch Sensors and Predictive Analysis via Large Language Models. [PDF]

Cureus
Momin EA, Mansoor H.
europepmc   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Educating older adults to use technologies for health management in social settings: perspectives of older adults and community workers. [PDF]

BMC Geriatr
Liu T, Luo Y, Pang P, Lau Y.
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

BEnchmarking Large Language Models for Ophthalmology (BELO): An Expert-Curated Data Set and Evaluation Framework for Knowledge and Reasoning. [PDF]

Ophthalmol Sci
Srinivasan S, Ai X, Lo TWS, Gilson A, Zou M, Zou K, Kim H, Yang M, Pushpanathan K, Yew SME, Loke WT, Goh JHL, Chen Y, Kong Y, Fu EY, Ong M, Nwanyanwu K, Dave A, Li KZ, Sun CH, Chia M, Yang GD, Wong WM, Chen DZ, Liu D, Singer M, Antaki F, Del Priore LV, Jonas JB, Adelman R, Chen Q, Tham YC.   +31 more
europepmc   +1 more source

Demonstration on Demonstrator Component

A technical report whereby the benefits of the PASSPORT software will be demonstrated by building a part using “best practice” versus the method from the ...
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source