Results 181 to 190 of about 27,380 (299)

Training medical students as basic life support instructors: a demonstrative method pilot study. [PDF]

Front Med (Lausanne)
Fernández Florido P, Parrilla Ruiz FM, Rodríguez Fernández de Simón T, Álamo García L, Gómez Moreno G, Pérez Villares JM, Cárdenas Cruz A.   +6 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

ARGscape: a modular, interactive tool for manipulation of spatiotemporal ancestral recombination graphs. [PDF]

Bioinformatics
Talbot CA, Bradburd GS.
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Syntactic change in diachrony versus contact-induced change: two sides of the same coin? [PDF]

Linguist Rev
D'Alessandro R, Putnam MT, Terenghi S.
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Architectural good practices for reproducible benchmarking in protein machine learning. [PDF]

Front Bioinform
García-Vinuesa J, Fernández-Villegas D, Soto-García M, Cadet X, Davari MD, Cadet F, Asenjo JA, Uribe-Paredes R, Medina-Ortiz D.   +8 more
europepmc   +1 more source

Demonstration on Demonstrator Component

A technical report whereby the benefits of the PASSPORT software will be demonstrated by building a part using “best practice” versus the method from the ...
openaire   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Impaired use of function words in European French-speaking children with developmental language disorder. [PDF]

Sci Rep
Le Normand MT, Thai-Van H.
europepmc   +1 more source