Results 211 to 220 of about 27,380 (299)

Construing Complex Referentiality in Interspecies Interaction: Embodiment and Biosemiotics. [PDF]

Animals (Basel)
Peltola R, Grandgeorge M.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The unfamiliar demonstrative in Dalabon

In this paper I describe the semantics and functions of the ‘unfamiliar’ demonstrative in Dalabon (Gunwinyguan, non-Pama-Nyungan). Demonstratives function to assist the addressee to identify a referent, prototypically by ‘pointing’ to the referent in the
Cutfield, S.
core  

Clinical demonstrations [PDF]

Postgraduate Medical Journal, 1972
openaire   +2 more sources

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Educating older adults to use technologies for health management in social settings: perspectives of older adults and community workers. [PDF]

BMC Geriatr
Liu T, Luo Y, Pang P, Lau Y.
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

BEnchmarking Large Language Models for Ophthalmology (BELO): An Expert-Curated Data Set and Evaluation Framework for Knowledge and Reasoning. [PDF]

Ophthalmol Sci
Srinivasan S, Ai X, Lo TWS, Gilson A, Zou M, Zou K, Kim H, Yang M, Pushpanathan K, Yew SME, Loke WT, Goh JHL, Chen Y, Kong Y, Fu EY, Ong M, Nwanyanwu K, Dave A, Li KZ, Sun CH, Chia M, Yang GD, Wong WM, Chen DZ, Liu D, Singer M, Antaki F, Del Priore LV, Jonas JB, Adelman R, Chen Q, Tham YC.   +31 more
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Frontotemporal dementia with right temporal predominance: a clinical comparison with left-predominant FTD. [PDF]

J Neurol
Thompson JC, Kobylecki C, Jones M, Haigh J, Larbey M, Langheinrich TC, Thomasson R, Richardson AMT, Snowden JS.   +8 more
europepmc   +1 more source