Results 261 to 270 of about 130,374 (337)

A new evidence-based design-of-experiments approach for optimizing drug delivery systems with exemplification by emulsion-derived Vancomycin-loaded PLGA capsules. [PDF]

Sci Rep
Namdar A, Borhanzadeh T, Salahinejad E.
europepmc   +1 more source

Clinical Research Tool Demonstration (Demonstrator)

This deliverable will document how the clinical research tool in the PIBD cloud environment has aided the aims and objectives of the PIBD project.
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Inferring Depression and Its Semantic Underpinnings from Simple Lexical Choices. [PDF]

Depress Anxiety
Kruse L, Rocca R, Wallentin M.
europepmc   +1 more source

Definiteness and specificity in Abui [PDF]

, 2015
Delpada, Benidiktus, Kratochvil, Frantisek   +1 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Ultrafast Spectroscopy of Commercial Sunscreen Formulations in Thin Films and on a Skin Mimic. [PDF]

ACS Omega
Whittock AL, Woolley JM, Cébrian J, Stavros VG, Rodrigues NDN.   +4 more
europepmc   +1 more source

The definite marker in Balinese [PDF]

, 2015
Artawa, Ketut, Shiohara, Asako
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Monitoring environmental heat on urban green infrastructure in central Italy based on the florence case study. [PDF]

Sci Rep
Frascella A, Guerri G, Crisci A, Dainelli M, Gonnelli C, Daniele V, Morabito M, Pignattelli S.   +7 more
europepmc   +1 more source