Results 101 to 110 of about 708 (251)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Editorial: Demonstratives, Deictic Pointing and the Conceptualization of Space. [PDF]

open access: yesFront Psychol, 2021
Diessel H   +3 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Speaker attitude and demonstrative choice in Ncane (Beboid)

open access: yesStudies in African Linguistics, 2018
Ncane is an underdocumented Bantoid language, which offers speakers multiple choices for referring to aforementioned participants. Anaphoric reference is usually made through a noun and an accompanying anaphoric demonstrative.
Richard L. Boutwell
doaj  

DEMONSTRATIONS [PDF]

open access: yesBritish Journal of Pharmacology, 1993
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Demonstrations [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1913
openaire   +2 more sources

Modalys demonstration

open access: yes, 2005
The IRCAM Musical Acoustics Team is not only focused on the muscial instrumetns modelisation research but also on the computer implementation of these models and the evaluation of the musical interest that the computer implementation may have. The physical modelling sound synthesis software Modalys is an environment where virtual acoustical instruments
Ellis, Nicholas   +2 more
openaire   +2 more sources

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