Results 281 to 290 of about 9,406,168 (354)
Clinical Utility of Serum Neurofilament Light Chain in Peripheral Neuropathy
ABSTRACT Introductions/Aims The clinical utility of serum neurofilament light chain (sNfL) in the evaluation and management of peripheral neuropathy (PN) remains poorly defined. This study aimed to evaluate the utility of sNfL for diagnosing PN, assessing disease activity, and monitoring treatment response using a commercially available assay.
Chafic Karam
wiley +1 more source
ABSTRACT Aim Treating multiple sclerosis (MS)‐related adult neurogenic lower urinary tract dysfunction (ANLUTD) is challenging because conservative treatments are often ineffective. Sacral neuromodulation (SNM) is a promising minimally invasive treatment of ANLUTD. This review assesses the efficacy and safety of SNM for MS‐related ANLUTD.
Carlos Ferreira +8 more
wiley +1 more source
GABA‐producing Lactococcus lactis protects against experimental autoimmune encephalomyelitis (EAE) in a mouse source‐dependent manner. The study focuses on the therapeutic potential of genetically engineered gamma‐aminobutyric acid (GABA)‐overproducing Lactococcus lactis (P8s‐GAD L. lactis) in the EAE model.
Kristina Hill +11 more
wiley +1 more source
The illustration indicates that increased BST2 expression in Schwann cells leads to cochlear nerve demyelination, accelerating hearing loss in ARHL. The upregulation of BST2 reduces POU6F1 expression by activating the NF‐κB pathway, which impairs MPZ transcription and Schwann cell migration, ultimately contributing to neural demyelination in ARHL ...
Mengxiao Liu +8 more
wiley +1 more source
This study shows that components of the ESCRT‐III membrane repair machinery, VPS4B and CHMP2A, are dysregulated in progressive MS and are associated with higher neurodegeneration and inflammation. This might lead to improper function of the complex to inhibit the final stages of necroptosis activation and thus impede neuronal cell death.
Carmen Picon +5 more
wiley +1 more source

