Results 281 to 290 of about 9,406,168 (354)

Clinical Utility of Serum Neurofilament Light Chain in Peripheral Neuropathy

open access: yesMuscle &Nerve, Volume 73, Issue 1, Page 86-92, January 2026.
ABSTRACT Introductions/Aims The clinical utility of serum neurofilament light chain (sNfL) in the evaluation and management of peripheral neuropathy (PN) remains poorly defined. This study aimed to evaluate the utility of sNfL for diagnosing PN, assessing disease activity, and monitoring treatment response using a commercially available assay.
Chafic Karam
wiley   +1 more source

Efficacy and Safety of Sacral Neuromodulation on Patients With Multiple Sclerosis and Lower Urinary Tract Dysfunction: A Systematic Review and Meta‐Analysis

open access: yesNeurourology and Urodynamics, Volume 45, Issue 1, Page 187-199, January 2026.
ABSTRACT Aim Treating multiple sclerosis (MS)‐related adult neurogenic lower urinary tract dysfunction (ANLUTD) is challenging because conservative treatments are often ineffective. Sacral neuromodulation (SNM) is a promising minimally invasive treatment of ANLUTD. This review assesses the efficacy and safety of SNM for MS‐related ANLUTD.
Carlos Ferreira   +8 more
wiley   +1 more source

Impact of a GABA‐Producing Lactococcus lactis on Microbiota and Mycobiota During CNS Inflammatory Demyelination

open access: yesFASEB BioAdvances, Volume 8, Issue 1, January 2026.
GABA‐producing Lactococcus lactis protects against experimental autoimmune encephalomyelitis (EAE) in a mouse source‐dependent manner. The study focuses on the therapeutic potential of genetically engineered gamma‐aminobutyric acid (GABA)‐overproducing Lactococcus lactis (P8s‐GAD L. lactis) in the EAE model.
Kristina Hill   +11 more
wiley   +1 more source

Melanoma Differentiation-Associated Gene 5 Is Critical for Protection against Theiler's Virus-Induced Demyelinating Disease

open access: yesJournal of Virology, 2011
Young-Hee Jin   +5 more
semanticscholar   +1 more source

Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age‐Related Hearing Loss via Enhancing Schwann Cell Migration

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
The illustration indicates that increased BST2 expression in Schwann cells leads to cochlear nerve demyelination, accelerating hearing loss in ARHL. The upregulation of BST2 reduces POU6F1 expression by activating the NF‐κB pathway, which impairs MPZ transcription and Schwann cell migration, ultimately contributing to neural demyelination in ARHL ...
Mengxiao Liu   +8 more
wiley   +1 more source

Dysregulation of the endosomal sorting complex III is linked to neurodegeneration in progressive multiple sclerosis

open access: yesBrain Pathology, Volume 36, Issue 1, January 2026.
This study shows that components of the ESCRT‐III membrane repair machinery, VPS4B and CHMP2A, are dysregulated in progressive MS and are associated with higher neurodegeneration and inflammation. This might lead to improper function of the complex to inhibit the final stages of necroptosis activation and thus impede neuronal cell death.
Carmen Picon   +5 more
wiley   +1 more source

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