Results 161 to 170 of about 44,319 (309)

Viruses and Demyelinating Diseases [PDF]

, 1985
D. Graham
openalex   +1 more source

Levodopa–Entacapone–Carbidopa Intrajejunal Infusion in Advanced Parkinson's Disease – Interim Analysis of the ELEGANCE Study

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Levodopa–entacapone–carbidopa intestinal gel (LECIG) was introduced in 2018 as a device‐aided therapy for advanced Parkinson's disease (PD). Objectives The ELEGANCE study (NCT05043103) is gathering real‐world data on long‐term efficacy, safety and patient‐reported outcomes with LECIG from 13 European countries.
Daniel Weiss, Wolfgang H. Jost, József Attila Szász, Zvezdan Pirtošek, Ivan Milanov, Volker Tomantschger, Norbert Kovács, Harry Staines, Bharat Amlani, Niall Smith, Teus van Laar   +10 more
wiley   +1 more source

Chemokine expression and viral infection of the central nervous system: regulation of host defense and neuropathology. [PDF]

, 2001
An effective host response against viral infection of the central nervous system (CNS) is the principal factor dictating the outcome of infection. It is the responsibility of the immune response to contain and control viral replication. Paradoxically, it
Lane, TE, Liu, MT
core  

Parkinsonism and neurosarcoidosis: Cause and effect or coincidence?

Clinical Parkinsonism & Related Disorders, 2019
Movement disorders in demyelinating diseases can be coincidental or secondary to a demyelinating lesion. We here report the first case of coincidental association of neurosarcoidosis and idiopathic Parkinson's disease.
Raja Mehanna, Lael Stone, Ilia Itin
doaj  

The impact of gut microbiome on neuro-autoimmune demyelinating diseases

Academia Biology
Demyelinating diseases, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and chronic inflammatory demyelinating polyneuropathy (CIDP), are characterized by dysregulated immune responses to self-antigens ...
Pouria Abolfazli, Cristina Nkene Apue Nchama, Brandon Lucke-Wold   +2 more
doaj   +1 more source

An X‐Linked Ataxia Syndrome in a Family with Hearing Loss Associated with a Novel Variant in the BCAP31 Gene

Movement Disorders, EarlyView.
Abstract Objective Pathogenic variants in B‐cell receptor‐associated protein (BCAP31) are associated with X‐linked, deafness, dystonia and cerebral hypomyelination (DDCH) syndrome. DDCH is congenital and non‐progressive, featuring severe intellectual disability (ID), variable dysmorphism, and sometimes associated with shortened survival. BCAP31 encodes
Martin Paucar, Tianyi Li, Åsa Bergendal, Irina Savitcheva, Kaveh Pourhamidi, José M. Laffita‐Mesa, Ann Nordgren, Martin Engvall, Per Uhlén, Kristina Lagerstedt‐Robinson, Per Svenningsson   +10 more
wiley   +1 more source

Acute small fiber neuropathy after Oxford‐AstraZeneca ChAdOx1‐S vaccination: A report of three cases and review of the literature

Journal of the Peripheral Nervous System, Volume 27, Issue 4, Page 325-329, December 2022., 2022
Abstract Small fiber neuropathy usually presents with gradual and progressive chronic length‐dependent pain. Acute small fiber neuropathy is rarely reported. Three patients with acute onset neuropathic pain after Oxford‐AstraZeneca ChAdOx1‐S vaccination are described.
Molly G. Abbott, Zahra Allawi, Monika Hofer, Olaf Ansorge, Stefen Brady, Ricardo Fadic, Gustavo Torres, Ravi Knight, Margarita Calvo, David L. H. Bennett, Andreas C. Themistocleous   +10 more
wiley   +1 more source

Investigation of neuro‐vascular reactivity on fMRI study during visual activation in people with multiple sclerosis using EEG and hypercapnia challenge

Medical Physics, EarlyView.
Abstract Background People with multiple sclerosis (MS) exhibit a different pattern of blood oxygenation level‐dependent (BOLD) activation on functional magnetic resonance imaging (fMRI) studies when compared to healthy control (HC). Purpose The objective of this study is to determine whether observed differences in BOLD activation between people with ...
Wanyong Shin, Balu Krishnan, Ajay Nemani, Daniel Ontaneda, Mark J. Lowe   +4 more
wiley   +1 more source

Rasch‐built overall disability scale for POEMS syndrome (POEMS‐RODS)

Journal of the Peripheral Nervous System, Volume 27, Issue 4, Page 302-310, December 2022., 2022
Abstract Patient‐reported outcome measures engage patients in disease severity measurement and the metrics reported can be meaningful to their lives. The Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein and Skin changes syndrome (POEMS) is a complex multisystem disorder with disabling neuropathy which is distinct from other acquired ...
Ryan Yann Shern Keh, James B. Lilleker, Tim Lavin, Jonathan Sive, Shirley D'Sa, Gita Ramdharry, Aisling S. Carr, Michael P. Lunn   +7 more
wiley   +1 more source

DomainScope: A disease network based on protein domain connections [PDF]

arXiv, 2019
Protein domains are highly conserved functional units of proteins. Because they carry functionally significant information, the majority of the coding disease variants are located on domains. Additionally, domains are specific units of the proteins that can be targeted for drug delivery purposes.
arxiv