Results 161 to 170 of about 9,029,710 (297)
The impact of gut microbiome on neuro-autoimmune demyelinating diseases
Academia BiologyDemyelinating diseases, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and chronic inflammatory demyelinating polyneuropathy (CIDP), are characterized by dysregulated immune responses to self-antigens ...
Pouria Abolfazli +2 more
doaj +1 more source
Cognitive Computation and Systems, EarlyView.Abstract Accurate magnetic resonance imaging (MRI) segmentation plays a critical role in the diagnosis and treatment of demyelinating diseases. But the existing automatic segmentation methods are not suitable for the segmentation of demyelinating lesions with small lesion size, highly diffuse edges and complex boundary shapes.
Minhui Liu +4 more
wiley +1 more source
T cell approach to demyelinating diseases [PDF]
, 1985 Hartmut Wekerle, Walter Fierz
openalex +1 more source
Research progress of idiopathic inflammatory demyelinating diseases
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018 Idiopathic inflammatory demyelinating diseases (IIDDs) belongs to autoimmune diseases of nervous system, which is a group of spectrum disorders including multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSDs), acute disseminated ...
Xiao-nan ZHONG, Xue-qiang HU
doaj
DomainScope: A disease network based on protein domain connections [PDF]
arXiv, 2019 Protein domains are highly conserved functional units of proteins. Because they carry functionally significant information, the majority of the coding disease variants are located on domains. Additionally, domains are specific units of the proteins that can be targeted for drug delivery purposes.
arxiv
Intermittent Fasting Enhances Motor Coordination Through Myelin Preservation in Aged Mice
Aging Cell, Volume 24, Issue 5, May 2025.Over a 10‐week regimen, IMF significantly improved locomotor activity, motor coordination, and muscle strength compared to controls (p < 0.01). Resting‐state fMRI (rsfMRI) demonstrated that IMF modulates brain‐wide functional connectivity, enhancing communication between key brain regions.
Zhuang Liu +12 more
wiley +1 more source
Aging Cell, Volume 24, Issue 5, May 2025.Age‐related differences in EAE outcomes stem from combined peripheral and CNS factors. Key peripheral adaptive immunity changes include altered naïve/memory T cell ratios, Th1 skewing, increased suppressive Tregs, CD4+ T cell exhaustion, enhanced B cell antigen presentation, and reduced NK cell cytotoxicity.
María Dema +6 more
wiley +1 more source
Myelin basic protein peptide 45–89 induces the release of nitric oxide from microglial cells.
, 2002 Continuous (24 h) exposure of mixed oligodendrocyte/microglial cells to peptides 45–89 derived from citrullinated C8 isoforms of myelin basic protein (MBP) induces cell death.
Machaidze, G. +4 more
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