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Demyelinating disease

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2013
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Superantigens in demyelinating disease

Springer Seminars in Immunopathology, 1996
Autoreactive T cells are part of the normal lymphocyte repertoire of healthy individuals [4]. In the immune system of healthy individuals, potent regulatory mechanisms control T and B cell tolerance to self antigens. While genetic factors influence susceptibility to autoimmunity in humans and experimental animals, environmental factors contribute to ...
Stefan Brocke   +2 more
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CNS demyelination in autoimmune diseases [PDF]

open access: possibleClinical Neurology and Neurosurgery, 2006
Autoimmune diseases represent a diverse group of disorders that have generally of unknown etiology and poorly understood pathogenesis. They may be organ-specific or systemic, giving rise to overlapping syndromes; more than one autoimmune disease may occur in the same patient.
Davorka Vranješ   +5 more
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Autoimmunity in Demyelinating Diseases

Annals of the New York Academy of Sciences, 1987
Demyelinative diseases of the CNS and peripheral nervous system can be distinguished on the basis of primary mediation by antibody or T lymphocytes (or failure of the T-cell-mediated response) and on the basis of chronicity. The principal mechanisms are autoimmunization to myelin antigens after actual immunization with tissue or infection with cross ...
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