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Olfactory Pathology in Central Nervous System Demyelinating Diseases
G. DeLuca+6 more
semanticscholar +1 more source
ABSTRACT Background and Aims The CMT Infant Scale (CMTInfS) enables evaluation of infants/toddlers in clinic. Our aim was to evaluate the feasibility, reliability, and validity of a virtual version of the CMTInfS (vCMTInfS). Methods Children aged 55 months or less were evaluated either in clinic using CMTInfS or remotely via telemedicine using the ...
Rosemary Shy+8 more
wiley +1 more source
ABSTRACT Background and Aims Validated objective measures for balance in immune mediated neuropathies are lacking. In this study, we investigated the clinimetric properties of posturography using a force platform, a quantitative assessment of postural control.
Milou R. Michael+5 more
wiley +1 more source
Family Game Show-style Didactic for Teaching Nervous System Disorders during Emergency Medicine Training [PDF]
Boysen Osborn, Megan+3 more
core
In the study, we employ an affordable, tissue‐saving, and precise simultaneous multiplex immunofluorescence method with heat‐induced antibody stripping to identify and structurally analyse nigral Lewy bodies in dopaminergic neurones. Analysis of different alpha‐synuclein epitopes and proteoforms reveals an almost uniform, onion‐like morphology of the ...
Dominik Hrabos+2 more
wiley +1 more source
Site-specific alteration of murine hepatitis virus type 4 peplomer glycoprotein E2 results in reduced neurovirulence [PDF]
Buchmeier, M J+3 more
core
Loss of ADAP1/CentA1 Protects Against Autoimmune Demyelination
ADAP1/CentA1 is an actin‐binding protein highly expressed in neurons. Our study describes a novel immunomodulatory function for ADAP1/CentA1 in the context of autoimmune demyelination. Mice lacking ADAP1/CentA1 were found partially resistant to the multiple sclerosis (MS) model experimental autoimmune encephalomyelitis (EAE) due to an altered ...
Jonathan J. Carver+6 more
wiley +1 more source
Recurrent asymptomatic demyelinating disease following 13-cis-retinoic acid exposure
Darin T. Okuda, Michael D. Prados
openalex +2 more sources
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The FASEB Journal, 2021
Current strategies for the treatment of demyelinating diseases such as multiple sclerosis (MS) are based on anti‐inflammatory or immunomodulatory drugs.
Laetitia Pouzol+8 more
semanticscholar +1 more source
Current strategies for the treatment of demyelinating diseases such as multiple sclerosis (MS) are based on anti‐inflammatory or immunomodulatory drugs.
Laetitia Pouzol+8 more
semanticscholar +1 more source