Results 271 to 280 of about 9,029,710 (297)

Olfactory Pathology in Central Nervous System Demyelinating Diseases

open access: yesBrain Pathology, 2015
G. DeLuca   +6 more
semanticscholar   +1 more source

Feasibility, Validity, and Reliability of the Virtual CMT Infant Toddler Scale (vCMTInfS): A Remote Evaluation of Infants/Toddlers With CMT

open access: yesJournal of the Peripheral Nervous System, Volume 30, Issue 2, June 2025.
ABSTRACT Background and Aims The CMT Infant Scale (CMTInfS) enables evaluation of infants/toddlers in clinic. Our aim was to evaluate the feasibility, reliability, and validity of a virtual version of the CMTInfS (vCMTInfS). Methods Children aged 55 months or less were evaluated either in clinic using CMTInfS or remotely via telemedicine using the ...
Rosemary Shy   +8 more
wiley   +1 more source

Validity and Responsiveness of Balance Measurements Using Posturography in Patients With Immune‐Mediated Neuropathies

open access: yesJournal of the Peripheral Nervous System, Volume 30, Issue 2, June 2025.
ABSTRACT Background and Aims Validated objective measures for balance in immune mediated neuropathies are lacking. In this study, we investigated the clinimetric properties of posturography using a force platform, a quantitative assessment of postural control.
Milou R. Michael   +5 more
wiley   +1 more source

Family Game Show-style Didactic for Teaching Nervous System Disorders during Emergency Medicine Training [PDF]

open access: yes, 2020
Boysen Osborn, Megan   +3 more
core  

Multiplex Immunofluorescent Analysis of Alpha‐Synuclein in Nigral Lewy Bodies With Heat‐Induced Antibody Stripping Reveals an Intricate Multilayered Structure

open access: yesNeuropathology and Applied Neurobiology, Volume 51, Issue 3, June 2025.
In the study, we employ an affordable, tissue‐saving, and precise simultaneous multiplex immunofluorescence method with heat‐induced antibody stripping to identify and structurally analyse nigral Lewy bodies in dopaminergic neurones. Analysis of different alpha‐synuclein epitopes and proteoforms reveals an almost uniform, onion‐like morphology of the ...
Dominik Hrabos   +2 more
wiley   +1 more source

Loss of ADAP1/CentA1 Protects Against Autoimmune Demyelination

open access: yesThe FASEB Journal, Volume 39, Issue 9, 15 May 2025.
ADAP1/CentA1 is an actin‐binding protein highly expressed in neurons. Our study describes a novel immunomodulatory function for ADAP1/CentA1 in the context of autoimmune demyelination. Mice lacking ADAP1/CentA1 were found partially resistant to the multiple sclerosis (MS) model experimental autoimmune encephalomyelitis (EAE) due to an altered ...
Jonathan J. Carver   +6 more
wiley   +1 more source
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ACT‐1004‐1239, a first‐in‐class CXCR7 antagonist with both immunomodulatory and promyelinating effects for the treatment of inflammatory demyelinating diseases

The FASEB Journal, 2021
Current strategies for the treatment of demyelinating diseases such as multiple sclerosis (MS) are based on anti‐inflammatory or immunomodulatory drugs.
Laetitia Pouzol   +8 more
semanticscholar   +1 more source

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