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Cytokines in Demyelinating Diseases
2008Abstract Among the autoimmune diseases, multiple sclerosis (MS) has been up to now best understood with regard to the pathogenesis of inflammation and demyelination, which affects the white matter of the brain. In MS brain are founded focal infiltrates of T cells and macrophages, axonal injury, and loss of neurological functions 1 , 2 , 3 .
Natalia M. Kalinina +1 more
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PATHOPHYSIOLOGY OF DEMYELINATING DISEASE [PDF]
British Medical Bulletin, 1977 A M Halliday, W I McDonald
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Mitochondrial Dysfunction in Demyelinating Diseases
Seminars in Pediatric Neurology, 2013Dysfunction of the mitochondrial (mt) system is thought to play an important role in the mechanism of progression of various neurodegenerative disorders, including demyelinating disorders. They are characterized by neuroinflammation, ultimately leading to neurodegeneration.
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