Results 121 to 130 of about 33,491 (200)

16S rRNA gene-based identification of bacteria in postoperative endophthalmitis by PCR-Denaturing Gradient Gel Electrophoresis (PCR-DGGE) fingerprinting. [PDF]

Braz J Microbiol, 2012
Navarro-Noya Y, Hernández-Rodríguez C, Zenteno JC, Buentello-Volante B, Cancino-Díaz ME, Jan-Roblero J, Cancino-Díaz JC.   +6 more
europepmc   +1 more source

Intranasal Administration of Isoeugenol Improves Memory Deficits in APP/PS1 Old Mice—A Role Beyond Nrf2 Activation?

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Inactivation of the Nrf2/Are pathway in AD leads to decreased antioxidant and anti‐inflammatory response and to the accumulation of beta‐amyloid (Aβ) plaques, resulting in cognitive failure. Treatment with Isoeugenol activates Nrf2, reversing these outcomes by promoting antioxidant response in neuronal cells (N2a) and by increasing the anti ...
Ana Silva, Sónia Silva, Jéssica Macedo, Patrícia Moreira, Diana Baptista, Joana Bicker, Ana Fortuna, Joana Liberal, Beatriz Rodrigues, Rosa Resende, Inês Vitorino, Armanda E. Santos, Bruno Miguel Neves, Cláudia Pereira, Maria Teresa Cruz   +14 more
wiley   +1 more source

Structural and Functional Insights Into (S)‐5′‐C‐Guanidinopropyl Uridine‐Modified Oligonucleotides With 2′‐O‐Methyl and 2′‐Fluoro Substitutions for RNAi Therapeutics

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Novel (S)‐5′‐guanidinopropyl uridine analogs bearing 2′‐O‐methyl or 2′‐fluoro substitutions enhance nuclease resistance and mismatch discrimination while preserving A‐form RNA structure and potent RNAi activity. These modifications provide a promising strategy for improving the stability, specificity, and therapeutic potential of siRNA‐based medicines.
Sugahara Masaki, Elsayed M. Mahmoud, Shuichi Sakamoto, Yoshihito Ueno   +3 more
wiley   +1 more source

Identification of bacteria in enrichment cultures of sulfate reducers in the Cariaco Basin water column employing Denaturing Gradient Gel Electrophoresis of 16S ribosomal RNA gene fragments. [PDF]

Aquat Biosyst, 2013
Bozo-Hurtado L, García-Amado MA, Chistoserdov A, Varela R, Narvaez JJ, Colwell R, Suárez P.   +6 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, Volume 16, Issue 8, Page 1491-1500, August 2026.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, Volume 13, Issue 43, 3 August 2026.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Identification of proteins exhibiting <i>in vitro</i> RNA chaperone activity through gradient profiling in the Lyme disease spirochete, <i>Borrelia burgdorferi</i>. [PDF]

RNA Biol
Van Gundy T, Schneider C, Ebmeier CC, Chambers GZ, Cramer NA, Chambers KM, Drecktrah D, Hyde JA, Skare JT, Marconi RT, Samuels DS, Lybecker MC.   +11 more
europepmc   +1 more source

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, Volume 13, Issue 43, 3 August 2026.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source

2'‐O‐Acetal Levulinic Ester Ribonucleoside 3'‐Phosphoramidites for the Solid‐Phase Synthesis of Long RNA

Current Protocols, Volume 6, Issue 8, August 2026.
Abstract Solid‐phase RNA synthesis is challenging because the 2'‐hydroxyl requires a protecting group that is stable during chain assembly yet easily removable without degrading the product. Driven by the demand for long RNA therapeutics, we report a synthesis method using 2'‐O‐acetal levulinic ester (ALE) ribonucleoside 3'‐O‐phosphoramidites.
Zidi Lyu, Adam Katolik, Masad J. Damha
wiley   +1 more source