Results 41 to 50 of about 54,130 (241)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Macroscopically uniform and flat lithium thin film formed by electrodeposition using multicomponent additives

Electrochemistry Communications, 2022
It is well-known that the electrodeposition of lithium usually results in the formation of dendrites on the electrode surface. This limits the utilization of metallic lithium as a material for, for example, the negative electrodes of rechargeable ...
Kazuhiro Fukami, Akihiro Sakurai, Takamitsu Tsujimoto, Masaki Yamagami, Atsushi Kitada, Kota Morimoto, Kiho Nishioka, Shuji Nakanishi, Yusuke Yoshikane, Toshimitsu Nagao, Jun-ichi Katayama, Kuniaki Murase   +11 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Designing sodium alloys for dendrite‐free sodium‐metal batteries

Information & Functional Materials
Sodium metal, with a high theoretical specific capacity (∼1165 mA h g−1) and a low redox potential (−2.71 V vs. SHE) as well as low cost, becomes an attractive option for high‐energy‐density sodium secondary batteries.
Kaitong Yao, Shitan Xu, Yang Yang, Yun Zheng, Karma Zuraqi, Dan Yang, Jue Liu, Ulaganathan Mani, Xianhong Rui   +8 more
doaj   +1 more source

Effectively Regulating More Robust Amorphous Li Clusters for Ultrastable Dendrite‐Free Cycling

Advanced Science, 2021
A disordered phase in Li‐deposit nanostructure is greatly attractive, but plagued by the uncontrollable and unstable growth, and the nanoscale characterization in the structure.
Shizhi Huang, Junfeng Yang, Luxiang Ma, Jingyi Ding, Xusheng Wang, Chengyuan Peng, Binglu Zhao, Mengxiong Cao, Junrong Zheng, Xin‐Xiang Zhang, Jitao Chen   +10 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Regulation of dendritic filopodial interactions by ZO-1 and implications for dendrite morphogenesis. [PDF]

PLoS ONE, 2013
Neuronal dendrites dynamically protrude many fine filopodia in the early stages of neuronal development and gradually establish complex structures. The importance of the dendritic filopodia in the formation of axo-dendritic connections is established ...
Ryouhei Komaki, Hideru Togashi, Yoshimi Takai   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source