Results 101 to 110 of about 51,515 (276)

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Free energy and dendritic self-organisation

Frontiers in Systems Neuroscience, 2011
In this paper, we pursue recent observations that, through selective dendritic filtering, single neurons respond to specific sequences of presynaptic inputs.
Stefan J Kiebel, Karl J Friston
doaj   +1 more source

Dendrite‐Free Sodium‐Metal Anodes for High‐Energy Sodium‐Metal Batteries

Advanced Materials, 2018
AbstractSodium (Na) metal is one of the most promising electrode materials for next‐generation low‐cost rechargeable batteries. However, the challenges caused by dendrite growth on Na metal anodes restrict practical applications of rechargeable Na metal batteries.
Bing Sun, Peng Li, Jinqiang Zhang, Dan Wang, Paul Munroe, Chengyin Wang, Peter H. L. Notten, Guoxiu Wang   +7 more
openaire   +4 more sources

Hydrogen‐Bond‐Rich Supramolecular Multiblock Copolymers Facilitate Rapid Zn2+ Migration in Quasi‐Solid‐State Zinc‐Ion Batteries

Advanced Functional Materials, EarlyView.
The disordered growth of dendrites, corrosion, parasitic side reactions, slow de‐solvation kinetics, and inherent safety risks significantly hinder the practical deployment of conventional liquid electrolyte zinc‐ion batteries. In contrast, the novel PU‐EG+DMPA‐Zn polyurethane quasi‐solid‐state electrolyte, enriched with abundant polar functional ...
Ruiqi Liu, Changding Wang, Fu Wan, Kaida Hu, Da Yang, Yaoyang Xia, Wenwei Yin, Yupeng Lin, Yuejiao Chen, Shuhui Sun, Weigen Chen   +10 more
wiley   +1 more source

Prospects of single atom catalysts for dendrite-free alkali metal batteries [PDF]

High-energy-density alkali metal batteries (AMBs) offer a potentially promising and sustainable option for energy storage. However, notorious dendrite growth and uncontrollable plating behaviors resulting from random spatial ion/atom distribution and ...
Guan, Qinghua, Jia, Lujie, Li, Huihua, Lin, Hongzhen, Qu, Hongxu, Wang, Jian, Zhang, Huang, Zhang, Jing   +7 more
core   +2 more sources

Grain Boundary Space Charge Engineering of Solid Oxide Electrolytes: Model Thin Film Study

Advanced Functional Materials, EarlyView.
This study demonstrates unprecedented control of grain boundary electrical properties in solid electrolytes. Selective diffusion of cations through grain boundaries in thin films enables 12 orders of magnitude variation in ionic resistance, proving that systematic chemical modification of grain boundary electrical properties is feasible.
Thomas Defferriere, Yong Beom Kim, Colin Gilgenbach, James M. LeBeau, WooChul Jung, Harry L. Tuller   +5 more
wiley   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Analysis of the Electrochemical Stability of Sulfide Solid Electrolyte Dry Films for Improved Dry‐Processed Solid‐State Batteries

Advanced Functional Materials, EarlyView.
An adapted processing for solvent‐free argyrodite solid electrolyte films based on insights into degradation mechanisms of the widely used binder polytetrafluoroethylene is presented. By adapting the dry film processing, long‐term cycling in Si||NMC pouch cells is demonstrated over more than 1000 cycles with a capacity retention of more than 80%, and ...
Maria Rosner, Sahin Cangaz, Felix Hippauf, Susanne Dörfler, Burak Aktekin, Thomas Meyer, Anja Henss, Thomas Abendroth, Holger Althues, Jürgen Janek, Stefan Kaskel   +10 more
wiley   +1 more source