Results 191 to 200 of about 48,857 (215)

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Regulation of dendrite growth and maintenance by exocytosis.

J Cell Sci, 2015
Peng Y, Lee J, Rowland K, Wen Y, Hua H, Carlson N, Lavania S, Parrish JZ, Kim MD.   +8 more
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Mechanically driven Li dendrite penetration in garnet solid electrolyte. [PDF]

Nature
Zhang Y, Motahari S, Woods EV, Zaefferer S, Schweizer P, Zhang Z, Liu Y, Gault B, Roters F, Raabe D, Scheu C, Joshi Y, Zhang S, Liu C, Dehm G.   +14 more
europepmc   +1 more source

Stochastic growth and ligand-receptor interaction-mediated stabilization generate stereotyped dendritic arbors. [PDF]

Nat Neurosci
Shi R, Ho XY, Tao L, Bayless-Edwards L, Taylor CA, Zhao T, Zou W, Lizzappi M, Eichel K, Mao T, Shen K.   +10 more
europepmc   +1 more source

Advanced Design of Three-Dimensional Lithiophilic Carbon-Based Hosts for Anode-Free Lithium Metal Batteries. [PDF]

Nanomicro Lett
Yang F, Yang X, Xu Z, Zhang M, Hou J, Yuan S, Zhang Y, Wu H, Zhang Y, Cheng F.   +9 more
europepmc   +1 more source

Role of Selected Organic Additives in Sulfate-Based Electroplating Baths for Copper Electrodeposition Toward Additive Manufacturing. [PDF]

Molecules
Kiesiewicz D, Syrek K, Niezgoda P, Pilch M.   +3 more
europepmc   +1 more source

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Unlocking the Electrochemical–Mechanical Coupling Behaviors of Dendrite Growth and Crack Propagation in All‐Solid‐State Batteries

Advanced Energy Materials, 2021
Chunhao Yuan, Wenquan Lu, Jun Xu
exaly  

Kinetics of lithium dendrite growth in garnet-type solid electrolyte

Journal of Power Sources, 2021
Changbao Zhu
exaly  

Lithium Dendrite in All-Solid-State Batteries: Growth Mechanisms, Suppression Strategies, and Characterizations

Matter, 2020
Daxian Cao, Xiao Sun, Avi Natan
exaly