Results 81 to 90 of about 7,799 (224)

Coexistence, crossover and extirpation in coalescent communities and ecotones

open access: yesOikos, EarlyView.
When two ecological communities come into contact, the strength of their mixing determines whether species coexist, extirpate, or extend their ranges. We present analytical formulas and simulations describing these transitions. Specifically, we derive abundance shifts upon community coalescence, identify the critical mixing strength leading to first ...
Martin Heidelman, Dervis Can Vural
wiley   +1 more source

Turbulent snow transport and accumulation: New reduced‐order models and diagnostics

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
Our new reduced‐order models of snow particle transport provide high‐fidelity calculations of snow accumulation in turbulent flows at significantly reduced computational costs. Additional accumulation diagnostics from the reduced‐order model predict complex patterns of particle concentration in turbulent boundary layers via coherent flow structures in ...
Nikolas O. Aksamit   +3 more
wiley   +1 more source

Information Dynamics and Learning in Complex Adaptive Systems: Toward a Transdisciplinary Framework

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT This article develops a framework for understanding learning and adaptation in complex adaptive systems. Drawing from neuroscience, systems theory, information theory and quantum field theory, it examines how information processing, plasticity and systemic coherence emerge from distributed, nonlinear and feedback‐driven interactions. It argues
Anderson de Souza Sant'Anna
wiley   +1 more source

Agglomeration Behavior of Nonmetallic Particles on the Surface of Si‐Killed Liquid Steel Using HT‐CSLM: An In Situ Investigation

open access: yessteel research international, EarlyView.
The in situ agglomeration behavior of semisolid Al–silicate inclusions in Si‐killed steel is studied using high‐temperature confocal scanning laser microscopy. Particle motion and interparticle forces at the steel/argon interface are quantified and compared with a modified capillary interaction model.
Suwam Kumar   +4 more
wiley   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

open access: yesVIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai   +11 more
wiley   +1 more source

Integrated Methylome–Transcriptome Analysis Reveals Epigenomic Remodeling and Rho GTPase–Linked Immune–Epithelial Crosstalk in Atopic Dermatitis

open access: yesAllergy, EarlyView.
Integrated methylome–transcriptome–microbiome analysis of AD skin identified thousands of DMRs. Rho GTPase signaling and actin–junctional programs emerged as central hubs integrating immune, epithelial, and microbial interactions in the pathogenesis of atopic dermatitis.
Tiina Skoog   +22 more
wiley   +1 more source

Infection control in the brain and the eye

open access: yesActa Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester   +2 more
wiley   +1 more source

An integrated approach to balance freshwater connectivity restoration and invasion risk

open access: yesConservation Biology, EarlyView.
Abstract Habitat fragmentation negatively affects many native migratory fish populations. However, this fragmentation can also prevent the spread and establishment of invasive species. We modified the dendritic connectivity index (DCI), a commonly used freshwater connectivity metric, to account for multiple invasive dispersal pathways in estimates of ...
Alex Arkilanian   +3 more
wiley   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

open access: yesThe FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti   +11 more
wiley   +1 more source

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