Results 21 to 30 of about 92,267 (298)

Morroniside ameliorates inflammatory skeletal muscle atrophy via inhibiting canonical and non-canonical NF-κB and regulating protein synthesis/degradation

open access: yesFrontiers in Pharmacology, 2022
No drug options exist for skeletal muscle atrophy in clinical, which poses a huge socio-economic burden, making development on drug interventions a general wellbeing need.
Xiangjiao Yi   +23 more
doaj   +1 more source

The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases [PDF]

open access: yes, 2013
[no ...
Abdala, Ana P   +13 more
core   +2 more sources

Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions

open access: yeseLife, 2015
Skeletal muscle maintenance depends on motor innervation at neuromuscular junctions (NMJs). Multiple mechanisms contribute to NMJ repair and maintenance; however muscle stem cells (satellite cells, SCs), are deemed to have little impact on these ...
Wenxuan Liu   +4 more
doaj   +1 more source

Selective ablation of the ligament of Marshall reduces ischemia and reperfusion-induced ventricular arrhythmias. [PDF]

open access: yesPLoS ONE, 2018
Cardiac sympathetic tone overdrive is a key mechanism of arrhythmia. Cardiac sympathetic nerves denervation, such as LSG ablation or renal sympathetic denervation, suppressed both the prevalence of VAs and the incidence of SCD.
Ruisong Ma   +8 more
doaj   +1 more source

The Range of Problematic Issues of Percutaneous Knee Denervation

open access: yesВестник анестезиологии и реаниматологии, 2022
Severe pain and, as a result, limitation of function are the main disabling factors in knee osteoarthritis. In such cases, percutaneous denervation (cryo- and chemoneurolysis, radiofrequency ablation) is used as one of the methods to reduce the intensity
D. A. Аveryanov   +4 more
doaj   +1 more source

Abnormal Reinnervation of Denervated Areas Following Nerve Injury Facilitates Neuropathic Pain

open access: yesCells, 2020
An injury to peripheral nerves leads to skin denervation, which often is followed by increased pain sensitivity of the denervated areas and the development of neuropathic pain.
Hodaya Leibovich   +8 more
doaj   +1 more source

Combined effects of functional overload and denervation on skeletal muscle mass and its regulatory proteins in mice

open access: yesPhysiological Reports, 2023
Skeletal muscle is a highly pliable tissue and various adaptations such as muscle hypertrophy or atrophy are induced by overloading or disuse, respectively. However, the combined effect of overloading and disuse on the quantitative adaptation of skeletal
Kazuki Uemichi   +2 more
doaj   +1 more source

The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension [PDF]

open access: yes, 2013
In the spontaneously hypertensive (SH) rat, hyperoxic inactivation of the carotid body (CB) produces a rapid and pronounced fall in both arterial pressure and renal sympathetic nerve activity (RSA).
Abdala, Ana P   +7 more
core   +2 more sources

Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates [PDF]

open access: yes, 2020
Perturbations in skeletal muscle metabolism have been reported for a variety of neuromuscular diseases. However, the role of metabolism after constriction injury to a nerve and the associated muscle atrophy is unclear.
Afzal, Shoaib   +3 more
core   +2 more sources

Fast-spiking GABA circuit dynamics in the auditory cortex predict recovery of sensory processing following peripheral nerve damage

open access: yeseLife, 2017
Cortical neurons remap their receptive fields and rescale sensitivity to spared peripheral inputs following sensory nerve damage. To address how these plasticity processes are coordinated over the course of functional recovery, we tracked receptive field
Jennifer Resnik, Daniel B Polley
doaj   +1 more source

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