Results 41 to 50 of about 5,722 (223)

A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans

Advanced Science, EarlyView.
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao, Yu‐Xin Zhang, Xiao‐Xing Liu, Zi‐Hang Li, Tang‐Sheng Lu, Jia‐Hui Deng, Wen Zhang, Peng Li, Xiao Lin, Shu‐Fei Feng, Ting‐Ting Li, Shi‐Qiu Meng, Xiang‐Dong Tang, Tian‐Ye Jia, Trevor W. Robbins, Jie Shi, Ying Han, Yan‐Xue Xue, Lin Lu, Kai Yuan   +19 more
wiley   +1 more source

Histopathological cancer images classification with Deng entropy

Biomedical Physics & Engineering Express
Abstract Histopathological imaging is of paramount importance for the initial detection, diagnosis, and classification of tumors. Recurrent neural networks and convolutional neural networks have led to substantial advancements in digital pathology, thereby enhancing classification accuracy.
Elva Estrada-Estrada, Aldo Ramirez-Arellano, Pilar Ortiz-Vilchis   +2 more
openaire   +2 more sources

A Novel Sensor Dynamic Reliability Evaluation Method and its Application in Multi-Sensor Information Fusion

IEEE Access, 2019
The improvement in recognition accuracy of a multi-sensor system is inseparable from the sensors' dynamic reliability, especially in the case of highly conflicting information. Recent research on multi-sensor system has shown that a difficult problem for
Jiali Weng, Fuyuan Xiao
doaj   +1 more source

Multisensor Data Fusion in IoT Environments in Dempster–Shafer Theory Setting: An Improved Evidence Distance-Based Approach

Sensors, 2023
In IoT environments, voluminous amounts of data are produced every single second. Due to multiple factors, these data are prone to various imperfections, they could be uncertain, conflicting, or even incorrect leading to wrong decisions. Multisensor data
Nour El Imane Hamda, Allel Hadjali, Mohand Lagha   +2 more
doaj   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Weighted Evidence Combination Based on Distance of Evidence and Entropy Function

International Journal of Distributed Sensor Networks, 2016
Conflict management in Dempster-Shafer theory (D-S theory) is a hot topic in information fusion. In this paper, a new weighted evidence combination on the basis of the distance between evidence and entropy function is presented.
Jianwei Wang, Fuyuan Xiao, Xinyang Deng, Liguo Fei, Yong Deng   +4 more
doaj   +1 more source

Paradox Elimination in Dempster–Shafer Combination Rule with Novel Entropy Function: Application in Decision-Level Multi-Sensor Fusion

Sensors, 2019
Multi-sensor data fusion technology in an important tool in building decision-making applications. Modified Dempster−Shafer (DS) evidence theory can handle conflicting sensor inputs and can be applied without any prior information.
Md Nazmuzzaman Khan, Sohel Anwar
doaj   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

Advanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang, Yimin Gong, Jianing Li, Tianze Wu, Mingli Deng, Yannan Yang   +5 more
wiley   +1 more source