Results 131 to 140 of about 754,759 (237)

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1212-1224, June 2026.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source

Development of MVA-d34 Tetravalent Dengue Vaccine: Design and Immunogenicity

open access: yes, 2023
Dengue fever, an infectious disease that affects more than 100 million people every year, is a global health problem. Vaccination may be the most effective prevention strategy for the disease.
Dina V. Glazkova   +6 more
core   +1 more source

The role of antibody-dependent enhancement in dengue vaccination

open access: yesTropical Diseases, Travel Medicine and Vaccines
Dengue is the most rapidly spreading vector-borne disease worldwide, with over half the global population at risk for an infection. Antibody-dependent enhancement (ADE) is associated with increased disease severity and may also be attributable to the ...
D. G. Aynekulu Mersha   +7 more
doaj   +1 more source

Community Awareness, Knowledge, Attitudes, and Perceptions Toward Viral Disease Outbreaks in Dar es Salaam, Tanzania

open access: yesPublic Health Challenges, Volume 5, Issue 2, June 2026.
High awareness of viral outbreaks in Dar es Salaam coexists with critical knowledge gaps, stigma, and vaccine hesitancy driven by trust and safety concerns. Targeted myth correction, anti‐stigma initiatives, and strategic digital health communication are essential to strengthen community preparedness and outbreak response.
Mohammed Elmogiera Fadlallh Elsayed   +2 more
wiley   +1 more source

Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines

open access: yes
Vox Sanguinis, EarlyView.
Pierre Tiberghien   +4 more
wiley   +1 more source

A Modular Design of a Cholera Toxin B Subunit‐Scaffolded Sub‐Virion Nanoparticle Vaccine Against West Nile Virus

open access: yesMicrobial Biotechnology, Volume 19, Issue 6, June 2026.
A recombinant West Nile virus (WNV) subunit vaccine was developed by displaying ED3 on a CTB scaffold. The fusion protein formed soluble nanoparticles in E. coli, eliciting strong, balanced, and specific neutralizing antibodies without cross‐reactivity, offering a safe, scalable subunit vaccine platform.
Hyun Byun   +13 more
wiley   +1 more source

Vaccination against dengue fever for travellers

open access: yesSwiss Medical Weekly
Dengue fever, endemic to most tropical and subtropical countries, is a major cause of illness in travellers, but severe dengue, hospitalisation and death are considered rare in this population.
Gilles Eperon   +3 more
doaj   +1 more source

Assessing Risk Thresholds in Controlled Human Infection Models (CHIM)

open access: yesBioethics, Volume 40, Issue 5, Page 519-529, June 2026.
ABSTRACT Controlled Human Infection Models (CHIMs) are a type of clinical trial involving deliberately exposing human volunteers to an infectious agent. Compared to studies of natural infection, CHIMs offers distinctive benefits, from the ability to study presymptomatic infection to a direct assessment of the efficacy of vaccines and therapeutics in a ...
Alexa Nord‐Bronzyk   +4 more
wiley   +1 more source

Update on Dengue Vaccines [PDF]

open access: yes
02-Dengue-Wong-508 ...

core  

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