Results 131 to 140 of about 754,759 (237)
Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley +1 more source
Development of MVA-d34 Tetravalent Dengue Vaccine: Design and Immunogenicity
Dengue fever, an infectious disease that affects more than 100 million people every year, is a global health problem. Vaccination may be the most effective prevention strategy for the disease.
Dina V. Glazkova +6 more
core +1 more source
The role of antibody-dependent enhancement in dengue vaccination
Dengue is the most rapidly spreading vector-borne disease worldwide, with over half the global population at risk for an infection. Antibody-dependent enhancement (ADE) is associated with increased disease severity and may also be attributable to the ...
D. G. Aynekulu Mersha +7 more
doaj +1 more source
High awareness of viral outbreaks in Dar es Salaam coexists with critical knowledge gaps, stigma, and vaccine hesitancy driven by trust and safety concerns. Targeted myth correction, anti‐stigma initiatives, and strategic digital health communication are essential to strengthen community preparedness and outbreak response.
Mohammed Elmogiera Fadlallh Elsayed +2 more
wiley +1 more source
Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines
Vox Sanguinis, EarlyView.
Pierre Tiberghien +4 more
wiley +1 more source
A recombinant West Nile virus (WNV) subunit vaccine was developed by displaying ED3 on a CTB scaffold. The fusion protein formed soluble nanoparticles in E. coli, eliciting strong, balanced, and specific neutralizing antibodies without cross‐reactivity, offering a safe, scalable subunit vaccine platform.
Hyun Byun +13 more
wiley +1 more source
Vaccination against dengue fever for travellers
Dengue fever, endemic to most tropical and subtropical countries, is a major cause of illness in travellers, but severe dengue, hospitalisation and death are considered rare in this population.
Gilles Eperon +3 more
doaj +1 more source
Assessing Risk Thresholds in Controlled Human Infection Models (CHIM)
ABSTRACT Controlled Human Infection Models (CHIMs) are a type of clinical trial involving deliberately exposing human volunteers to an infectious agent. Compared to studies of natural infection, CHIMs offers distinctive benefits, from the ability to study presymptomatic infection to a direct assessment of the efficacy of vaccines and therapeutics in a ...
Alexa Nord‐Bronzyk +4 more
wiley +1 more source

