Results 121 to 130 of about 157,517 (252)

What are the vector species of the Oropouche virus?

open access: yesPest Management Science, Volume 82, Issue 4, Page 2785-2793, April 2026.
Here, we review the timeline of Oropouche virus (OROV) detection in various hematophagous Diptera, from 1955 to date, including mosquitoes and midges. All vector competence experiments also are described. The results suggest that Culicoides are the primary vectors.
Constância Flávia Junqueira Ayres   +3 more
wiley   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

open access: yesBiological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning   +19 more
wiley   +1 more source

CRISPR‐Enhanced RAA‐SHERLOCK Assay for Point‐of‐Care Detection of Cyprinid Herpesvirus‐3: Development, Validation and Clinical Application

open access: yesJournal of Fish Diseases, Volume 49, Issue 4, April 2026.
ABSTRACT Koi herpesvirus disease (KHVD), caused by Cyprinid herpesvirus‐3 (CyHV‐3), poses a significant threat to global aquaculture due to its high mortality rates and economic impact. Current diagnostic methods, such as PCR, are limited by equipment dependency and procedural complexity, hindering point‐of‐care (POC) applications.
Hatem Soliman, Naveed Akram, Mona Saleh
wiley   +1 more source

Rapid Detection and Molecular Typing of Dengue Virus by Using Multiplex-Nested-RT-PCR

open access: yesIndonesian Journal of Biotechnology, 2015
world. We have evaluated the combination of one-step RT-PCR and multiplex nested PCR assays for detectingdengue viruses from clinical samples. Twelve patients were screened for the dengue virus, using a pair of primersthat conserve for several Flavivirus.
Nastiti Wijayanti   +4 more
doaj  

Enhancing Dengue Virus Production and Immunogenicity with Celcradle™ Bioreactor: A Comparative Study with Traditional Cell Culture Methods

open access: yesVaccines
The dengue virus, the primary cause of dengue fever, dengue hemorrhagic fever, and dengue shock syndrome, is the most widespread mosquito-borne virus worldwide.
Hongxia Guo   +11 more
doaj   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel   +2 more
wiley   +1 more source

Attenuation and immunogenicity of recombinant yellow fever 17D-dengue type 2 virus for rhesus monkeys

open access: yesBrazilian Journal of Medical and Biological Research, 2005
A chimeric yellow fever (YF)-dengue serotype 2 (dengue 2) virus was constructed by replacing the premembrane and envelope genes of the YF 17D virus with those from dengue 2 virus strains of Southeast Asian genotype.
Galler R.   +9 more
doaj  

Label‐Free Detection of PSA Using Laser‐Induced Graphene/ZnO Nanorod‐Based Impedimetric Immunosensors

open access: yesAdvanced Sensor Research, Volume 5, Issue 3, March 2026.
A label‐free impedimetric immunosensor based on laser‐induced graphene decorated with ZnO nanorods is developed for prostate‐specific antigen detection. Antibody adsorption on ZnO enables clinically relevant sensitivity and an unconventional “signaling‐off” response, where charge‐transfer resistance decreases upon antigen binding, challenging ...
Maria S. Soares   +4 more
wiley   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz   +10 more
wiley   +1 more source

Acute Urticaria as the Sole Manifestation of Dengue Fever: A Rare Case Report

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Urticaria is a very uncommon dermatological manifestation of infection by the dengue virus. It can hinder diagnosis since some of its features overlap with allergic conditions, such as maculopapular and petechial rashes. We present a case of a 32‐year‐old male, resident of a dengue‐endemic area, who presented with an acute onset of generalized
Md Osman Goni   +6 more
wiley   +1 more source

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