Results 21 to 30 of about 3,297 (182)

Single-dose HPV vaccination efficacy among adolescent girls and young women in Kenya (the KEN SHE Study): study protocol for a randomized controlled trial

open access: yesTrials, 2021
Background HPV infection is the primary cause of cervical cancer, a leading cause of cancer among women in Kenya and many sub-Saharan African countries. High coverage of HPV vaccination is a World Health Organization priority to eliminate cervical cancer
Ruanne V. Barnabas   +17 more
doaj   +1 more source

Development and testing of a polygenic risk score for breast cancer aggressiveness

open access: yesnpj Precision Oncology, 2023
Aggressive breast cancers portend a poor prognosis, but current polygenic risk scores (PRSs) for breast cancer do not reliably predict aggressive cancers. Aggressiveness can be effectively recapitulated using tumor gene expression profiling.
Yiwey Shieh   +22 more
doaj   +1 more source

On architectural rormalism and social concern: a discourse for social planners and radical chic architects [PDF]

open access: yes, 2020
On architectural formalism and social concern: A discourse for social planners and radical chic architects. Publicado originalmente en Oppositions #5, 1976. Traducción de Álvaro Martínez. Introducción al artículo en pàg.
Martínez, Álvaro, Scott Brown, Denise
core   +1 more source

Components of Adolescent Behavioural Interventions With Eating Disorder Outcomes: Systematic Review With Intervention Mapping. [PDF]

open access: yesPediatr Obes
ABSTRACT Objective To understand delivery features and intervention strategies of adolescent weight management interventions which may influence eating disorder risk. Methods Systematic searches in four databases and two trial registries to identify randomised controlled trials in adolescents with overweight/obesity measuring eating disorder risk pre ...
Lister NB   +50 more
europepmc   +2 more sources

Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer

open access: yesnpj Breast Cancer, 2022
HSP90 inhibitors destabilize oncoproteins associated with cell cycle, angiogenesis, RAS-MAPK activity, histone modification, kinases and growth factors.
Julie E. Lang   +48 more
doaj   +1 more source

Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2+ breast cancer in the adaptively randomized I-SPY2 trial

open access: yesNature Communications, 2021
HER2-targeted therapy improves patient’s outcome in early breast cancer. Here, the authors present the efficacy and biomarker analysis of two HER2-targeted combinations (ado-trastuzumab emtansine plus pertuzumab and paclitaxel, trastuzumab and pertuzumab)
Amy S. Clark   +50 more
doaj   +1 more source

Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer

open access: yesnpj Breast Cancer, 2021
I-SPY2 is an adaptively randomized phase 2 clinical trial evaluating novel agents in combination with standard-of-care paclitaxel followed by doxorubicin and cyclophosphamide in the neoadjuvant treatment of breast cancer.
Douglas Yee   +54 more
doaj   +1 more source

Urbanismo y género. Las mujeres dentro del canon urbanístico: de la excepción positiva a la exclusión sistemática

open access: yesArea, 2020
El objetivo de este trabajo es ofrecer algunas interpretaciones para analizar el canon del urbanismo desde una perspectiva de género. La disciplina no escapa a la tendencia general de desigualdad en el acceso al campo profesional, conformando y ...
Octavio Fernández Álvarez
doaj   +2 more sources

Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study

open access: yesEBioMedicine, 2022
Summary: Background: Better understanding of the association between characteristics of patients hospitalized with coronavirus disease 2019 (COVID-19) and outcome is needed to further improve upon patient management.
Al Ozonoff   +338 more
doaj   +1 more source

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